Results 191 to 200 of about 256,119 (304)

Machine Learning‐Derived Immune Gene Signature Predicts Prognosis and Therapeutic Vulnerabilities in Multiple Myeloma

Cancer Science, EarlyView.
An immune‐related 12‐gene signature developed through integrative machine learning stratified overall survival across multiple myeloma cohorts and remained independently associated with outcome. Single‐cell, somatic mutation, and transcriptome‐based drug‐response analyses further linked the signature to multicellular bone marrow context, distinct ...
Kai Wang, Chenfei Zhao, Jingru Shi, Shiwei Liu, Yi Chen, Jujuan Wang, Zhengxu Sun, Sanmei Wang, Lei Fan, Jin Fan, Xiaoyan Qu   +10 more
wiley   +1 more source

Melatonin and Indole-3-Propionic Acid Reduce Surface FcγRIII/CD16-Related Parameters in Porcine Peripheral Blood Mononuclear Cells In Vitro. [PDF]

Int J Mol Sci
Śliwka PW, Stępniak J, Karbownik-Lewińska M.   +2 more
europepmc   +1 more source

Cord Blood‐Derived Fibroblast Activation Protein‐Targeted Chimeric Antigen Receptor Natural Killer Cells Persist in Vivo

Cancer Science, EarlyView.
We generated cord blood‐derived FAP‐targeted CAR NK cells and evaluated their activity against cancer‐associated fibroblasts. These cells showed antigen‐specific cytotoxicity in vitro and robust persistence in a pleural dissemination model, although in vivo anti‐CAF efficacy was limited, supporting further development of stromal‐targeted cellular ...
Takashi Hiroshima, Toru Kimura, Mariko Maekawa, Mayuko Noguchi, Takahiro Matsui, Shunya Ikeda, Makiko Suga, Hideki Nagata, Kenji Kimura, Eriko Fukui, Takashi Kanou, Naoko Ose, Eiichi Morii, Yasushi Shintani, Naoki Hosen   +14 more
wiley   +1 more source

Citrullinated histone H3 and elevated polyamine metabolism gene expression in peripheral blood polymorphonuclear leukocytes as biomarkers for poor immunotherapy response in cancer patients. [PDF]

Mol Biomed
Anzovino A, Kjelstrom S, Fleck K, Wallon M, Alexander ET, Gilmour SK.   +5 more
europepmc   +1 more source

Short-interval longitudinal analysis of immune cell dynamics in heavy draft foals after colostrum intake. [PDF]

J Vet Med Sci
Yoshida S, Takeyama A, Maeda Y, Nambo Y.
europepmc   +1 more source

Tattoo Inflammation With Uveitis: From Recognition to Definition

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Tattoo inflammation with uveitis (TIU) is increasingly recognised but growing case numbers have revealed substantial heterogeneity. Patients currently classified as TIU appear to include those with overt or evolving systemic sarcoidosis as well as those with isolated, pigment‐associated ocular inflammation.
Anthea Anantharajah, Nicolas Kluger, Anthony J. H. Hall, Michelle Sharp, Jennifer E. Thorne, Lyndell L. Lim   +5 more
wiley   +1 more source

Unexpected Cardiotocographic Deterioration in Fetal Transient Abnormal Myelopoiesis. [PDF]

Cureus
Tanaka K, Yamaguchi M, Sakata J, Motohara T, Kondoh E.   +4 more
europepmc   +1 more source

Optimising Haematopoietic Stem Cell Transplantation: Enhancing Myeloablation Sensitivity and Alleviating Anaemia Using Roxadustat (FG‐4592)

Cell Proliferation, EarlyView.
The use of FG‐4592 in the process of myeloablation can promote haematopoietic cell apoptosis for more effective myeloablation, maintain the number of RBC and may create a pluripotent microenvironment suitable for donor cells, so as to enable more effective haematopoietic reconstruction of donor cells in vivo.
Guanheng Yang, Jiahui Wu, Xinbing Guo, Wenchen Shen, Xiao Sang, Xiuli Gong, Shu‐Zhen Huang, Jingzhi Zhang, Fanyi Zeng   +8 more
wiley   +1 more source

Analysis of Cytological Markers of Cellular Senescence in High-Risk Cardiovascular Patients After COVID-19. [PDF]

Biomed Res Int
Kyryk V, Ustymenko A, Tsupykov O, Skarzhevskyi O, Parkhomenko O.   +4 more
europepmc   +1 more source