DNA Methylation Profile in Human Cord Blood Mononuclear Leukocytes From Term Neonates: Effects of Histological Chorioamnionitis [PDF]
Frontiers in Pediatrics, 2020 Background: Histological chorioamnionitis (HCA) is an infection/inflammation of fetal membranes and complicates 5.2–28.5% of all live births. Exposure to HCA can have long-term consequences including abnormal neurodevelopment and an increased risk for ...
Gina Fong +11 more
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Chemokine-Decorated Nanoparticles Target Specific Subpopulations of Primary Blood Mononuclear Leukocytes [PDF]
Nanomaterials, 2022 Specific cell targeting to deliver nanoparticles can be achieved by tailored modifications of the material surface with chemical moieties. The selection of the cell targets can be optimized by covering the nanoparticle with molecules, the receptor ...
Anissa Pisani +5 more
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Cytokine Profile in Human Peripheral Blood Mononuclear Leukocytes Exposed to Immunoadjuvant and Adjuvant-Free Vaccines Against Influenza [PDF]
Frontiers in Immunology, 2020 Background: In the last decade, adjuvant-containing vaccines, exerting different effects on the immune system, including the production of cytokines, which are one of the most important regulatory systems of the body, are introduced into practice ...
Mikhail Petrovich Kostinov +4 more
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Andrographolide Inhibits Expression of NLPR3 Inflammasome in Canine Mononuclear Leukocytes [PDF]
AnimalsInflammasomes are multiprotein complexes that trigger processes through caspase-1 activation, leading to the maturation of proinflammatory cytokines, such as IL-1β and IL-18.
Alejandro Albornoz +8 more
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Enhanced serum interferon-lambda 1/interleukin-29 levels in patients with psoriasis vulgaris
Anais Brasileiros de Dermatologia, 2021 Background: Interferon (IFN)-λ1, also named Interleukin (IL)-29, is a new member of the Type III IFN or IFN-λ family. IL-29 plays an important role in the pathogenesis of many types of autoimmune and inflammatory diseases.
Li-xin Fu +5 more
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Optimizing viable leukocyte sampling from the female genital tract for clinical trials: an international multi-site study. [PDF]
PLoS ONE, 2014 Functional analysis of mononuclear leukocytes in the female genital mucosa is essential for understanding the immunologic effects of HIV vaccines and microbicides at the site of HIV exposure.
Lyle R McKinnon +25 more
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Neural Regeneration Research, 2022 Antipsychotics may prolong or retain telomere length, affect mitochondrial function, and then affect the metabolism of nerve cells. To validate the hypothesis that antipsychotics can prolong telomere length after oxidative stress injury, leukocytes from ...
Gabriel B Polho +7 more
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Arthritis Research & Therapy, 2023 Background Soluble urate leads to a pro-inflammatory phenotype in human monocytes characterized by increased production of IL-1β and downregulation of IL-1 receptor antagonist, the mechanism of which remains to be fully elucidated.
Viola Klück +9 more
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Histological assessment of the efficiency of rabbit serum in healing skin wounds [PDF]
Veterinary World, 2019 Aim: This study aimed to investigate the impact of rabbit serum on skin wound healing with the help of histological examination. Materials and Methods: A total of ten indigenous rabbits were used in this study. The animals were divided into two groups:
Abeer Ahmed Majeed, Dhyaa Ab. Abood
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Бюллетень сибирской медицины, 2020 Aim. To study the level of activity of lysosomal cysteine proteases (cathepsins H, B, L) in blood plasma and fractionated leukocytes (polymorphonuclear and mononuclear) in patients with Alzheimer’s disease in comparison with similar indicators in persons
M. G. Sorokina +3 more
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