Results 31 to 40 of about 128,260 (307)

LEPTIN AS AN INDUCER OF INFLAMMATION AND OXIDATIVE STRESS BY METABOLIC SYNDROME

open access: yesБюллетень сибирской медицины, 2014
Object of research: to explore the relationship of leptin level in blood serum with markers of systemic inflammation and spontaneous production of cytokines and reactive oxygen species by blood mononuclear leukocytes at metabolic syndrome.Material and ...
I. D. Bespalovа
doaj   +1 more source

Identifying chemokines as therapeutic targets in renal disease: Lessons from antagonist studies and knockout mice [PDF]

open access: yes, 2004
Chemokines, in concert with cytokines and adhesion molecules, play multiple roles in local and systemic immune responses. In the kidney, the temporal and spatial expression of chemokines correlates with local renal damage and accumulation of chemokine ...
Abdi R   +34 more
core   +1 more source

Down-regulation of cholesterol biosynthesis in sitosterolemia: diminished activities of acetoacetyl-CoA thiolase, 3-hydroxy-3-methylglutaryl-CoA synthase, reductase, squalene synthase, and 7-dehydrocholesterol Δ7-reductase in liver and mononuclear leukocytes

open access: yesJournal of Lipid Research, 1998
Sitosterolemia is a recessively inherited disorder characterized by abnormally increased plasma and tissue plant sterol concentrations. Patients have markedly reduced whole body cholesterol biosynthesis associated with suppressed hepatic, ileal, and ...
Akira Honda   +5 more
doaj   +1 more source

Immunological response of human leucocytes after exposure to lipopolysaccharides from Porphyromonas gingivalis

open access: yesClinical and Experimental Dental Research, 2021
Porphyromonas gingivalis (P. gingivalis) is a gram‐negative bacterium and an important etiologic agent of periodontitis. P. gingivalis releases outer membrane vesicles containing lipopolysaccharides (LPS), which can penetrate periodontal tissues. Once in
Sara Alizadehgharib   +4 more
doaj   +1 more source

How periodontal disease may contribute to cardiovascular disease [PDF]

open access: yes, 2000
No abstract ...
Kinane, D.F., Lowe, G.D.O.
core   +1 more source

An Altered Metabolism in Leukocytes Showing in vitro igG Memory From SARS-CoV-2-Infected Patients

open access: yesFrontiers in Molecular Biosciences, 2022
Coronavirus disease 2019 (COVID 19) is a systemic infection that exerts a significant impact on cell metabolism. In this study we performed metabolomic profiling of 41 in vitro cultures of peripheral blood mononuclear cells (PBMC), 17 of which displayed ...
G. Fanelli   +6 more
doaj   +1 more source

Polyomaviruses BK and JC DNA infection in peripheral blood cells from blood donors

open access: yesBrazilian Journal of Infectious Diseases, 2019
Objectives: To investigate the prevalence of human polyomavirus (BK and JC viruses) infection in peripheral blood mononuclear cells of healthy blood donors. Methods: The study included 250 healthy blood donors.
Malihe Fathi Haghighi   +7 more
doaj   +1 more source

A Mitochondrial Health Index Sensitive to Mood and Caregiving Stress. [PDF]

open access: yes, 2018
BACKGROUND:Chronic life stress, such as the stress of caregiving, can promote pathophysiology, but the underlying cellular mechanisms are not well understood.
Aschbacher, Kirstin   +7 more
core   +1 more source

Secretome Profiling of Atlantic Salmon Head Kidney Leukocytes Highlights the Role of Phagocytes in the Immune Response to Soluble β-Glucan

open access: yesFrontiers in Immunology, 2021
β‐Glucans (BG) are glucose polymers which are produced in bacteria and fungi but not in vertebrate organisms. Being recognized by phagocytic leukocytes including macrophages and neutrophils through receptors such as dectin-1 and Complement receptor 3 ...
Dimitar B. Iliev   +5 more
doaj   +1 more source

Aggregation of mononuclear and red blood cells through an α4β1-Lu/basal cell adhesion molecule interaction in sickle cell disease

open access: yesHaematologica, 2010
Background Abnormal interactions between red blood cells, leukocytes and endothelial cells play a critical role in the occurrence of the painful vaso-occlusive crises associated with sickle cell disease.
Vicky Chaar   +9 more
doaj   +1 more source

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