Results 31 to 40 of about 80,122 (306)

LEPTIN AS AN INDUCER OF INFLAMMATION AND OXIDATIVE STRESS BY METABOLIC SYNDROME

Бюллетень сибирской медицины, 2014
Object of research: to explore the relationship of leptin level in blood serum with markers of systemic inflammation and spontaneous production of cytokines and reactive oxygen species by blood mononuclear leukocytes at metabolic syndrome.Material and ...
I. D. Bespalovа
doaj   +1 more source

Down-regulation of cholesterol biosynthesis in sitosterolemia: diminished activities of acetoacetyl-CoA thiolase, 3-hydroxy-3-methylglutaryl-CoA synthase, reductase, squalene synthase, and 7-dehydrocholesterol Δ7-reductase in liver and mononuclear leukocytes

Journal of Lipid Research, 1998
Sitosterolemia is a recessively inherited disorder characterized by abnormally increased plasma and tissue plant sterol concentrations. Patients have markedly reduced whole body cholesterol biosynthesis associated with suppressed hepatic, ileal, and ...
Akira Honda, Gerald Salen, Lien B. Nguyen, G. Stephen Tint, Ashok K. Batta, Sarah Shefer   +5 more
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Immunological response of human leucocytes after exposure to lipopolysaccharides from Porphyromonas gingivalis

Clinical and Experimental Dental Research, 2021
Porphyromonas gingivalis (P. gingivalis) is a gram‐negative bacterium and an important etiologic agent of periodontitis. P. gingivalis releases outer membrane vesicles containing lipopolysaccharides (LPS), which can penetrate periodontal tissues. Once in
Sara Alizadehgharib, Anna‐Karin Östberg, Agnes Dahlstrand Rudin, Ulf Dahlgren, Karin Christenson   +4 more
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In Vitro Generation of Procoagulant Activity by Corynebacterium parvum-Stimulated Mononuclear Leukocytes [PDF]

, 1985
Thromboembolic complications are known in cancer patients after i.v. administration of Corynebacterium parvum. We examined the ability of this organism to induce production of procoagulant activity by human blood mononuclear leukocytes in vitro.
G Ricci, D Fumarola, G Miragliotta, G Barone, C Marcuccio   +4 more
core   +1 more source

An Altered Metabolism in Leukocytes Showing in vitro igG Memory From SARS-CoV-2-Infected Patients

Frontiers in Molecular Biosciences, 2022
Coronavirus disease 2019 (COVID 19) is a systemic infection that exerts a significant impact on cell metabolism. In this study we performed metabolomic profiling of 41 in vitro cultures of peripheral blood mononuclear cells (PBMC), 17 of which displayed ...
G. Fanelli, F. Gevi, G. Zarletti, M. Tiberi, V. De Molfetta, G. Scapigliati, A. M. Timperio   +6 more
doaj   +1 more source

Increased Expression of Cell-Cell Signaling Genes by Stimulated Mononuclear Leukocytes in Patients with Previous Atherothrombotic Stroke A Whole Genome Expression Profile Study [PDF]

, 2009
Background/Aims: Inflammation plays an important role in atherosclerosis and stroke. Acute infections are recognized as trigger factors for ischemic stroke. Methods: In this whole genome expression profile study of 15 patients and 15 control subjects, we
Wiest, Tina, Horstmann, Solveig, Honold, Cornelius, Hergenhahn, Manfred, Mansmann, Ulrich, Wagner, Simone, Weninger, Annette, Pfleger, Karin, Grond-Ginsbach, Caspar, Hollstein, Monika, Grau, Armin J., Hummel, Manuela, Knyazev, Yuri   +12 more
core   +1 more source

Decreased levels of B-endorphin in circulating mononuclear leukocytes from patients with acute myocardial infarction [PDF]

, 1998
Lymphocytes can be activated to produce and release opioid peptides. We investigated the levels of immunoreactive β-endorphin in peripheral blood mononuclear cells from 11 patients with acute myocardial infarction.
A.E. PANERAI, C. PECHLANER, M. JOANNIDIS, C. J. WIEDERMANN, T. BURATTI, P. SACERDOTE, S. E. MANFREDA, S. DUNZENDORFER, P. SHRATZENBERGER   +8 more
core   +1 more source

Polyomaviruses BK and JC DNA infection in peripheral blood cells from blood donors

Brazilian Journal of Infectious Diseases, 2019
Objectives: To investigate the prevalence of human polyomavirus (BK and JC viruses) infection in peripheral blood mononuclear cells of healthy blood donors. Methods: The study included 250 healthy blood donors.
Malihe Fathi Haghighi, Noorossadat Seyyedi, Ali Farhadi, Farahnaz Zare, Leila Kasraian, Gholam Reza Refiei Dehbidi, Reza Ranjbaran, Abbas Behzad-Behbahani   +7 more
doaj   +1 more source

Aggregation of mononuclear and red blood cells through an α4β1-Lu/basal cell adhesion molecule interaction in sickle cell disease

Haematologica, 2010
Background Abnormal interactions between red blood cells, leukocytes and endothelial cells play a critical role in the occurrence of the painful vaso-occlusive crises associated with sickle cell disease.
Vicky Chaar, Julien Picot, Olivier Renaud, Pablo Bartolucci, Ruben Nzouakou, Dora Bachir, Frédéric Galactéros, Yves Colin, Caroline Le Van Kim, Wassim El Nemer   +9 more
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Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source