Results 51 to 60 of about 80,122 (306)

Theileria annulata and T. parva infect and transform different bovine mononuclear cells [PDF]

, 1989
Bovine peripheral blood mononuclear cells (PBMC) were labelled with monoclonal antibodies recognizing bovine MHC class II, sIgM, monocyte, T-helper and T-cytotoxic cell phenotypes.
Brown, C G, Innes, E A, Spooner, R L, Glass, E J   +3 more
core  

Modification of platelet aggregation by leukocytes in acute ischemic stroke. [PDF]

, 1994
Platelet aggregation plays an important role in the pathogenesis of thromboembolic cerebrovascular disease. Leukocytes can efficiently stimulate as well as inhibit platelet aggregability.
R Sigmund, W Hacke, A J Grau
core   +1 more source

Mitochondrial redox impairment and enhanced autophagy in peripheral blood mononuclear cells from type 1 diabetic patients

Redox Biology, 2022
Type 1 diabetes (T1D) involves critical metabolic disturbances that contribute to an increased cardiovascular risk. Leukocytes are key players in the onset of atherosclerosis due to their interaction with the endothelium.
F. Canet, P. Díaz-Pozo, C. Luna-Marco, M. Fernandez-Reyes, T. Vezza, M. Marti, J.D. Salazar, I. Roldan, C. Morillas, S. Rovira-Llopis, M. Rocha, V.M. Víctor   +11 more
doaj   +1 more source

Tropomyosin 1 Promotes Platelet Adhesion and Clot Contraction Separate from Its Roles in Developmental Hematopoiesis

Advanced Science, EarlyView.
ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung, Victor Tsao, Alina D Peshkova, Oscar A. Marcos‐Contreras, Kim Ha, Brian M Dulmovits, Nkemdilim Okoli, Anvi Sinha, Gennadiy Fonar, Rong Qiu, Rolf D Bates, Janelle Yeboah, Carson Shalaby, Tyler Truex, Soomin Jeong, Edna C Hardeman, Peter W Gunning, Vladimir R Muzykantov, Jacob W Myerson, Christopher S Thom   +19 more
wiley   +1 more source

Mineralocorticoid effector mechanism of liquorice derivatives in human mononuclear leukocytes. [PDF]

, 1989
The mineralocorticoid effector mechanism of glycyrrhetinic acid and of its ester derivative carbenoxolone was evaluated in human mononuclear leukocytes by radioreceptorassay and measurement of intracellular sodium and potassium after incubation of the ...
WEHLING M, WEBER PC, ARMANINI, DECIO
core  

Low-Density-Lipoprotein Receptor and 3-Hydroxy-3-Methylglutaryl Coenzyme-A Reductase Gene-Expression in Human Mononuclear Leukocytes Is Regulated Coordinately and Parallels Gene-Expression in Human Liver [PDF]

, 1994
The liver plays a key regulatory role in cholesterol metabolism. Two proteins are central in this role; the LDL receptor and 3-hydroxy-3-methylglutaryl CoA reductase (HMG CoA reductase), the rate-limiting enzyme in cholesterol biosynthesis.
Powell, EE, P A Kroon, E E Powell, Kroon, PA   +3 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Monoclonal antibody identification of infiltrating mononuclear leukocytes in lupus nephritis [PDF]

, 1986
Monoclonal antibody identification of infiltrating mononuclear leukocytes in lupus nephritis (LN). Populations of mononuclear inflammatory cells infiltrating the renal interstitium in LN were studied by means of an avidin–biotin immunoperoxidase ...
Knowles, Daniel M., D'Agati, Vivette D., Appel, Gerald B., Estes, Dorothy, Pirani, Conrad L.   +4 more
core   +1 more source

Macro- and microelements of blood mononuclear leukocytes in patients withpulmonary tuberculosis

Бюллетень сибирской медицины, 2007
In article the results of the analysis of changes of the contents macro- and microelements (К+, Ca2+, Fe2+, Cu2+, Mn2+, Zn2+, Mg2+, Al3+) in lymphocytes and monocytes of peripheral blood in patients with infiltrative drug-sensitive and drug-resistant ...
V. V. Novitsky, A. K. Strelis, O. I. Ourazova, T. A. Shilko, S. B. Tkachenko, I. Ye. Yesimova, O. V. Voronkova, V. A. Serebryakova, O. V. Filinyuk, Ye. V. Ivanova, O. V. Baranova   +10 more
doaj   +1 more source

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source