Results 71 to 80 of about 80,122 (306)

Surface LSP-1 Is a Phenotypic Marker Distinguishing Human Classical versus Monocyte-Derived Dendritic Cells

open access: yesiScience, 2020
Summary: Human mononuclear phagocytes comprise several subsets of dendritic cells (DCs), monocytes, and macrophages. Distinguishing one population from another is challenging, especially in inflamed tissues, owing to the promiscuous expression of ...
Sandrine Moutel   +7 more
doaj   +1 more source

Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes

open access: yesAdvanced Science, EarlyView.
PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami   +15 more
wiley   +1 more source

Bovine colostrum and immune function after exercise [PDF]

open access: yes, 2012
Strenuous and/or prolonged exercise causes transient perturbations in immune function. It is well accepted that this is one mechanism contributing to the higher occurrence of infection (e.g.
Glen Davison, Davison, Glen
core   +1 more source

In vitro cholesterol synthesis in freshly isolated mononuclear cells of human blood: effect of in vivo administration of clofibrate and/or cholestyramine.

open access: yesJournal of Lipid Research, 1980
The rate of incorporation of [2-14C]acetate into cholesterol has been measured in freshly isolated peripheral blood mononuclear leukocytes from patients on various hypolipidemic drugs that affect whole body cholesterol synthesis.
D J McNamara, N O Davidson, S Fernandez
doaj   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng   +7 more
wiley   +1 more source

1,25-dihydroxyvitamin D3 and development of tuberculosis in cattle [PDF]

open access: yes, 2003
This report describes the presence and activity of 1,25-dihydroxyvitamin D3 (1,25-D3) in experimental bovine tuberculosis. Animals that went on to develop tuberculous lesions exhibited a rapid transient increase in serum 1,25-D3 within the first 2 weeks ...
Hewinson, R. G.   +4 more
core  

REGULATION OF IMMUNE HOMEOSTASIS OF THE HUMAN INTESTINE BY METABOLITES OF BIFIDOBACTERIA UNDER CONDITIONS OF MICROBIAL RECOGNITION

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2017
Aim. To study the production of cytokins on the model of peripheral blood lymphocytes under the activity of Bifidobacterium bifidum 791 strain induced by Lactobacillus fermentum 90T-C4, Escherichia coli 157 and Staphylococcus aureus 209 metabolites ...
O. V. Bukharin   +2 more
doaj   +1 more source

Chitotriosidase activity in plasma and mononuclear and polymorphonuclear leukocyte populations [PDF]

open access: yesJournal of Clinical Laboratory Analysis, 2003
AbstractIn the general population, about 5% of individuals are homozygotic and 35% are heterozygotic carriers for chitotriosidase (ChT) deficiency. Activated macrophages are considered to be the main source of plasma ChT activity, which permits the biochemical characterization of homozygote deficients.
Lorena, Bouzas   +2 more
openaire   +2 more sources

Condition‐Associated Pattern Extraction and Recovery From Multi‐Condition Single‐Cell RNA‐seq Data With CAPER

open access: yesAdvanced Science, EarlyView.
Decoupling biological signals from unwanted variation in multi‑condition single‑cell RNA sequencing data remains challenging. CAPER disentangles condition‑associated biological effects from sample heterogeneity through matrix factorization, producing interpretable latent factors and a batch‑corrected expression matrix.
Ye Li   +6 more
wiley   +1 more source

[3H]CGP-17177 Binding to ß-adrenoceptors of intact bovine mononuclear leukocytes [PDF]

open access: yes, 1993
Saturation and inhibition binding studies, using [H-3]CGP-12177 as radioligand, reveal the presence of a single class of beta-adrenoceptors on intact bovine mononuclear leukocytes.
Burvenich, Christian Paul G.   +2 more
core  

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