Results 91 to 100 of about 80,122 (306)

Some hematological characteristics of adenomyosis

Гинекология, 2013
In the given work are presented some hematological criteria of diagnostics of adenomyosis, is also explored opportunities to use the results of studies of the population composition of blood leukocytes and its relationship poly - and mononuclear cells in
M R Orazov
doaj  

Engineering Human Donor Derived Germinal Center‐Like Organoids (GCLOs) for Studying Immune Response to Vaccination

Advanced Science, EarlyView.
We bioengineered a new approach methodology of generating Germinal Center Organoids that self‐organize from human blood‐derived immune cells. These immune organoids reproduce key features of humoral immunity, IgG production, and plasmablast emergence.
Bhumi Suthar, Carlos Gomez, Giancarlo Asencio, Suresh Pallikkuth, Ashutosh Agarwal   +4 more
wiley   +1 more source

Targeting the ATX‐LPA Axis Overcomes TKI Resistance and Immunosuppression in Renal Cell Carcinoma via Dual Inhibition of AKT/mTOR and TBK1/IRF3 Pathways

Advanced Science, EarlyView.
ABSTRACT Background Therapeutic resistance limits durable survival in advanced/metastatic renal cell carcinoma (RCC) treated with first‐line tyrosine kinase inhibitor (TKI) plus immune checkpoint inhibitor (ICI). We sought to define key resistance drivers and actionable targets.
Jinchen Luo, Hansen Lin, Haoqian Feng, Lei Tan, Xi Liu, Yong Huang, Junjie Cen, Jiajie Chen, Xinwei Zhou, Mingjie Lin, Wuyuan Liao, Zheyu Ai, Minyu Chen, Yinghan Wang, Wei Chen, Junhang Luo, Yanping Liang   +16 more
wiley   +1 more source

The role of galectin-1 and galectin-3 in the mechanisms of T-cell immune response dysregulation in colon cancer

Бюллетень сибирской медицины, 2020
The aim of the study was to characterize the features of the subpopulation composition and cytokine-secretory activity of T lymphocytes (Th1, Th17 and Treg) in relation to the concentration of galectin-1 and galectin-3 in the blood of patients with colon
V. S. Poletika, Yu. V. Kolobovnikova, O. I. Urazova, O. A. Vasileva, A. I. Dmitrieva, K. I. Yankovich, V. V. Novitsky, L. M. Ryabova, M. Yu. Grishchenko   +8 more
doaj   +1 more source

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

Mononuclear Leukocyte Cyclic Adenosine Monophosphate Responses in Psoriasis Are Normal [PDF]

, 1984
It has been proposed that immune dysfunction in psoriasis is a consequence of aberrent cyclic nucleotide metabolism. We have examined cyclic AMP responses to isoprenaline, histamine, and prostaglandin E2 in peripheral blood mononuclear leukocytes from ...
Macdonald, D.M., Hanson, Jennifer M, Morley, J., Archer, C B   +3 more
core   +1 more source

Leukocyte and Platelet Characteristics of the Giant Panda (Ailuropoda melanoleuca): Morphological, Cytochemical, and Ultrastructural Features

Frontiers in Veterinary Science, 2020
The giant panda (Ailuropoda melanoleuca) is a vulnerable species and a charismatic member of zoological collections worldwide. Despite its importance as a representative species for global wildlife conservation efforts, no studies to date have described ...
Spencer P. Kehoe, Nicole I. Stacy, Salvatore Frasca, Tracy Stokol, Chengdong Wang, Kathryn Strayer Leach, Li Luo, Sam Rivera   +7 more
doaj   +1 more source

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Parallel determination of glucocorticoid receptors in human mononuclear and polymorphonuclear leukocytes after Percoll separation. [PDF]

, 1985
Circulating human leukocytes are known to possess glucocorticoid receptors, but the data in the literature on the affinity and capacity widely range. We here report our results on the determination of affinity and capacity of glucocorticoid receptors in ...
WEBER P.C., ARMANINI, DECIO, STRASSER T
core  

Antioxidant effects of anthocyanins-rich extract from black sticky rice on human erythrocytes and mononuclear leukocytes [PDF]

, 2015
The present study was aimed at determining the optimum dose of anthocyanins-rich extract (ARE) from Thai pigmented rice for its antioxidant effects. Three different methods of antioxidant analysis [Oxygen Radical Absorbance Capacity (ORAC) assay, Folin ...
Tencomnao, Tewin, Sangkitikomol, Warin, Rocejanasaroj, Atittaya   +2 more
core   +2 more sources