Ancestry Matters in Decoding Immunity
The Chinese Immune Multi‐Omics Atlas (CIMA) establishes a population‐scale immune multi‐omics atlas by profiling over 10 million peripheral blood mononuclear cells from 428 Chinese adults using paired scRNA‐seq and scATAC‐seq. This resource mitigates longstanding European ancestry bias in single‐cell genomics and enables cell type resolved regulatory ...
Kesong Wu +2 more
wiley +1 more source
Molecular Diversity and Functional Implications of Mammalian Choline Acetyltransferases in Neuronal and Non-Neuronal Cells. [PDF]
Marinova D, Trifonov S.
europepmc +1 more source
Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger +5 more
wiley +1 more source
SIRT2 Regulates EX VIVO PBMC Adhesion in Septic Shock Patients. [PDF]
Shrestha D +12 more
europepmc +1 more source
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag +6 more
wiley +1 more source
Major Traumatic and Severe Thermal Injuries Lead to Immediate and Persistent Elevations in Circulating Concentrations of Resistin That Are Associated with Poor Clinical Outcomes and Impaired Innate Immune Responses. [PDF]
Horner E +14 more
europepmc +1 more source
Clinical &Experimental Allergy, EarlyView.
Jessica Cristiane da Conceição de Andrade +14 more
wiley +1 more source
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed +6 more
wiley +1 more source
Accurate Quantification of Platelets and Leukocytes in Platelet-Rich Fibrin Using Direct Fibrinolytic Digestion: Effects of Centrifugation Protocols on Cellular Composition and Fibrin Architecture. [PDF]
Apaiso P +3 more
europepmc +1 more source
The Role of Oxidative Stress in Periodontitis
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon +3 more
wiley +1 more source

