Results 51 to 60 of about 128,249 (313)

T-cell subpopulations αβ and γδ in cord blood of very preterm infants : The influence of intrauterine infection [PDF]

, 2013
Open Access: This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are creditedPreterm infants are very ...
A Kotiranta-Ainamo, Agata Serwatowska-Bargieł, B Mazur, BJ Stoll, C Cairo, C Koehler, C Nakasone, CL Langrish, DJ Sherman, DL Gibbons, E Juretic, Elżbieta Górska, ER Newton, F Jouen-Beades, G Locksmith, GA Follows, H Zaghouani, J Chipeta, L Marodi, M Snyder, Maria Katarzyna Kornacka, Maria Wąsik, N Xiong, NC Maxwell, PJ Duggan, R Romero, RA Polin, RL Goldenberg, RL Schelonka, Robert Kozarski, RS Baltimore, S Beetz, SC Rosa De, T Matsuoka, TA Moore, Y Konigshofer, Y Zhao   +36 more
core   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

IMMUNOLOGICAL AND METABOLIC FACTORS INTERACTION IN THE DEVELOPMENT AND PROGRESSION OF MICROVASCULAR COMPLICATIONS IN LATENT AUTOIMMUNE DIABETES OF ADULTS (LADA)

Бюллетень сибирской медицины, 2014
Some researchers found that the development of microvascular complications (nephropathy, retinopathy) with latent autoimmune diabetes adults (LADA) occurs much earlier than in type 1 diabetes mellitus.
T. V. Saprina, T. S. Prokhorenko, F. E. Lazarenko, I. N. Vorozhtsova, N. V. Ryazantseva   +4 more
doaj   +1 more source

Mitochondrial redox impairment and enhanced autophagy in peripheral blood mononuclear cells from type 1 diabetic patients

Redox Biology, 2022
Type 1 diabetes (T1D) involves critical metabolic disturbances that contribute to an increased cardiovascular risk. Leukocytes are key players in the onset of atherosclerosis due to their interaction with the endothelium.
F. Canet, P. Díaz-Pozo, C. Luna-Marco, M. Fernandez-Reyes, T. Vezza, M. Marti, J.D. Salazar, I. Roldan, C. Morillas, S. Rovira-Llopis, M. Rocha, V.M. Víctor   +11 more
doaj   +1 more source

Characterisation of nicotine receptors on human peripheral blood mononuclear cells (PBMC) [PDF]

, 2009
“The original publication is available at www.springerlink.com”. Copyright Springer. DOI: 10.1007/s00011-008-8171-xAim and objective: The aim of the work was to characterise the nAChRs on human PBMC.
Parsons, M., Whelan, C.J., Wongsriraksa, A.   +2 more
core   +1 more source

Macrophage Membrane‐Cloaked, ROS‐Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome

Advanced Healthcare Materials, EarlyView.
The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li, Yu Guan, Nan Song, Feng Zhang, Zhimin Deng, Tailang Yin, Yanbing Yang, João Conde, Wenyi Jin, Zhinang Yin   +9 more
wiley   +1 more source

Collection and composition of autologous peripheral blood stem cells graft in patients with acute myeloid leukemia: influence on hematopoietic recovery and outcome [Skupljanje i sastav transplantata autolognih krvotvornih matičnih stanica periferne krvi u bolesnika s akutnom mijeloičnom leukemijom: utjecaj na hematološki oporavak i ishod] [PDF]

, 2010
Hematopoietic stem cell (HSC) transplantation is a standard approach in the treatment of hematological malignant diseases. For the last 15 years the main source of cells for trasplantation have been peripheral blood stem cells (PBSC).
Batinić, Drago, Bojanić, Ines, Dubravčić, Klara, Dušak, Vesna, Golubić-Ćepulić, Branka, Labar, Boris, Mazić, Sanja, Mrsić, Mirando, Nemet, Damir, Raos, Mirela, Sertić, Dubravka, Serventi-Seiwerth, Ranka   +11 more
core  

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Formation of eyeball orbital stump using titanium nickelide tissue-engineered construct and autologous blood mononuclear leukocytes

Вестник трансплантологии и искусственных органов, 2020
Objective: to study the morphological features of formation of the eyeball orbital stump using a titanium nickelide  tissue-engineered construct and a suspension of autologous blood mononuclear leukocytes in vivo. Materials  and methods. Experiments were
E. A. Gorbunova, O. I. Krivosheina, L. R. Mustafina   +2 more
doaj   +1 more source

Increased Expression of Cell-Cell Signaling Genes by Stimulated Mononuclear Leukocytes in Patients with Previous Atherothrombotic Stroke A Whole Genome Expression Profile Study [PDF]

, 2009
Background/Aims: Inflammation plays an important role in atherosclerosis and stroke. Acute infections are recognized as trigger factors for ischemic stroke. Methods: In this whole genome expression profile study of 15 patients and 15 control subjects, we
Grau, Armin J., Grond-Ginsbach, Caspar, Hergenhahn, Manfred, Hollstein, Monika, Honold, Cornelius, Horstmann, Solveig, Hummel, Manuela, Knyazev, Yuri, Mansmann, Ulrich, Pfleger, Karin, Wagner, Simone, Weninger, Annette, Wiest, Tina   +12 more
core   +1 more source