Results 201 to 210 of about 221,944 (307)

Reduced Circulating Regulatory T Cells in Autoimmune and Chronic Idiopathic Neutropenia of Childhood: An Observational Study of Clinical and Laboratory Associations

European Journal of Haematology, EarlyView.
ABSTRACT Objectives To investigate circulating regulatory T cells (Tregs) in children with autoimmune neutropenia (AIN) and chronic idiopathic neutropenia (CIN) and evaluate their associations with clinical and laboratory features of neutropenia. Methods Plasma and Peripheral Blood Mononuclear Cells (PBMCs) were collected from 69 participants.
Konstantina Toutoudaki, Elena E. Solomou, Marianna Tzanoudaki, Stavros Glentis, Panagiota Perari, Panagiota Davoulou, Eftichia Theodoropoulou, Polyxeni Delaporta, Eleni Stamou, Irene Mavroudi, Charalambos Pontikoglou, Helen Papadaki, Antonis Kattamis   +12 more
wiley   +1 more source

Delphinidin Exerts Immunomodulatory Effects in Canine Neutrophils and Peripheral Blood Mononuclear Cells by Limiting Tissue Damaging Mechanisms and Regulating Cytokine Responses. [PDF]

Animals (Basel)
Hidalgo AI, Vega M, Maldonado D, Teuber S, Burgos RA, Hidalgo MA.   +5 more
europepmc   +1 more source

From hepatic to hematopoietic: LRH‐1's expanding cellular repertoire to the immune system

The FEBS Journal, EarlyView.
The nuclear receptor LRH‐1 is a well‐characterized regulator of endodermal tissue. Yet, increasing evidence indicates that LRH‐1, although expressed at low levels, is also a critical regulator of the hematopoietic system. LRH‐1 regulates the immune system by contributing to immune cell‐specific functions.
Lukas Meisinger, Alice Wiedmann, Rayan Hassan M. Elshikhidriss, Thomas Brunner   +3 more
wiley   +1 more source

Platelet-specific P2Y₁ receptor deficient mice have suppressed pulmonary leukocyte recruitment in response to lipopolysaccharide. [PDF]

Respir Res
Pan D, Lino-Alvarado A, Amison RT, Oralman T, Evans R, Baker O, Cocks G, Page CP, Pitchford SC.   +8 more
europepmc   +1 more source

Updates and controversies in contemporary grading of clear cell renal cell carcinoma and papillary renal cell carcinoma

Histopathology, EarlyView.
New concepts, innovations and some issues have emerged since the adoption a decade ago of WHO/ISUP grading for CCRCC and PRCC. Continued use of the WHO/ISUP grading for CCRCC and PRCC has been upheld by newer studies, and practice guidance for some of the grading issues, where data are available, is provided.
Gladell P. Paner, Mahul. B. Amin, Jung Woo Kwon, Liang Cheng, Holger Moch   +4 more
wiley   +1 more source

Accurate Quantification of Platelets and Leukocytes in Platelet-Rich Fibrin Using Direct Fibrinolytic Digestion: Effects of Centrifugation Protocols on Cellular Composition and Fibrin Architecture. [PDF]

Biomedicines
Apaiso P, Nimlamool W, Daroontum T, Sangin S.   +3 more
europepmc   +1 more source

CD68 and F4/80 Markers Demonstrate Inflammatory Synergism Between Apical Periodontitis and Liver Fibrosis in Wistar Rats

International Endodontic Journal, EarlyView.
ABSTRACT Aim To evaluate CD68 and F4/80 glycoproteins in the worsening of apical periodontitis (AP) and liver fibrosis (LF) in Wistar rats. Methodology Thirty‐two Wistar rats were distributed in the following groups (n = 8): C—control; AP—apical periodontitis; LF—liver fibrosis; APLF—AP and LF.
L. V. Barroti, C. Cantiga‐Silva, M. P. Justo, P. H. C. Oliveira, F. D. Faria, J. Goto, E. Ervolino, G. Sivieri‐Araújo, T. N. Pinheiro, L. T. A. Cintra   +9 more
wiley   +1 more source

Pathological insights of human CD34+ hematopoietic stem cell-engrafted NSG mice: Implications for the safety assessment of cancer immunotherapy drugs. [PDF]

Vet Pathol
Giusti AM, Sam J, Colombetti S, Veiga IB, Monné Rodríguez JM.   +4 more
europepmc   +1 more source

Ovarian Cancer‐Associated Ascites Accumulates NK Lymphocytes Displaying a Transcriptomic Profile Consistent With the Immature/Secretory CD56bright Subtype

Immunology &Cell Biology, EarlyView.
NK cells present in EOC‐associated ascites retain elements of the conventional NK cell program while displaying a transcriptional profile distinct from peripheral blood NK cells. This profile encompasses biological programs usually associated with the CD56bright NK cell functions, which is consistent with transcriptional remodeling rather than complete
Caroline Natânia de Souza‐Araújo, Glenerson Baptista, Gabriela Rapozo Guimarães, Raissa Carolina Alves da Silva, Adriana Yoshida, Cláudia Rodrigues Tonetti, José Andrés Yunes, Daniela Maira Cardoso, Sophie Derchain, Mariana Boroni, Fernando Guimarães   +10 more
wiley   +1 more source

Diabetes exacerbates destructive inflammation by activating the CD137L-CD137 axis in dendritic and IL-17+ T cells. [PDF]

J Clin Invest
Huang X, Liu M, Gonzalez MV, Debnath R, Afzali H, Choi Y, Kim SA, Ko KI, Graves DT.   +8 more
europepmc   +1 more source