Results 141 to 150 of about 221,944 (307)

The In Vitro Effects of Choline on Non-Esterified Fatty Acid-Treated Bovine Peripheral Blood Leukocytes

Animals
The transition period is defined as 3 weeks around parturition, involving the rapid increase in the energy demand, promoting adipose mobilization and non-esterified fatty acid (NEFA) release.
Cheng-Yan Li, Yueh-Tung Chen, Tossapol Moonmanee, Jacky Peng-Wen Chan, Chien-Kai Wang   +4 more
doaj   +1 more source

Demonstration of membrane-bound proteolytic activity on the surface of mononuclear leukocytes

, 1981
The existence of proteolytic enzymes bound to the surface of migrating cells has often been surmised. That such enzymes are present on mononuclear leukocytes was suggested by studies showing that serum amyloid A (SAA), the presumed precursor of amyloid ...
G Lavie, EC Franklin, D Zucker-Franklin
core   +1 more source

Adverse immunostimulation in early phase clinical trials: Key findings and recommendations based on the investigator's clinical experience

British Journal of Clinical Pharmacology, EarlyView.
Problem setting The emergence of therapeutic proteins has coincided with an increase of acute adverse immunostimulation (AIS). AIS has occured in clinical trials despite compliance with regulatory guidelines on preclinical evaluation and its incidence is anticipated to increase even further.
Juliette A. van den Noort, Marella C. E. van Ruissen, Lisanne C. A. Smidt, Naomi B. Klarenbeek, Philip H. K. Kremer, Manon A. A. Jansen, Jacobus Burggraaf, Joop M. A. van Gerven, Matthijs Moerland   +8 more
wiley   +1 more source

[The role of mononuclear leukocytes in the pathogenesis of glomerulonephritis].

Terapevticheskii arkhiv, 1991
To specify the role of mononuclear (MN) leukocytes in the development of mesangial cell proliferation, which is one of the main manifestations of glomerulonephritis, cell cultures of renal glomeruli of rats with nephrotoxic serum (NTS) nephritis were examined for the intensity of mesangial cell proliferation, the MN-leukocyte count, and for IL-1 ...
E M, Shilov, O V, Gabrilevskaia, A A, Ivanov, O P, Gladskikh, V P, Leskov, M A, Pal'tsev, I E, Tareeva   +6 more
openaire   +1 more source

Carrier‐free self‐assembled nanomedicine for combination‐therapy of acute myeloid leukemia

BMEMat, EarlyView.
CPDS combines drugs with three different mechanisms of action to achieve a multi‐mechanism combination therapy for AML by directly killing tumor cells and activating anti‐tumor immunity. Abstract As the main acute myeloid leukemia (AML) clinical treatment, the chemotherapy alone cannot meet the clinical therapeutic needs due to the high heterogeneity ...
Meihong Chai, Rui Zhang, Haiyin Yang, Jiyue Xing, Tianyuan Hu, Mengxi Zhu, Rui Li, Xiaoli Chen, Beibei Zhao, Yang Lan, Stefan Barth, Yuanyu Huang, Li Zhang, Mengjie Zhang, Huining He   +14 more
wiley   +1 more source

O. anthropi recruits leukocytes in the peritoneum.

, 2013
Groups of 6 mice were intraperitoneally inoculated with 106 CFU/ml of O. anthropi. Thereafter, peritoneal exudates were obtained and leukocytes counted.
Ignacio Moriyón (32148), Lucía Quesada-Lobo (372221), Mateja Mancek-Keber (5653786), Edgardo Moreno (32149), Roman Jerala (165758), Jean Pierre Gorvel (372222), Elías Barquero-Calvo (32142), Carlos Chacón-Díaz (32146), Esteban Chaves-Olarte (32143), Maite Iriarte (51187), Anna Martirosyan (119494), Raquel Conde-Alvarez (5653783), Caterina Guzmán-Verri (32145)   +12 more
core   +1 more source

Characterization of the Immune Response after Oral Cholera Vaccination (OCV) and Effects of Mycophenolate Mofetil on Priming of this Immune Response—A Randomized, Placebo‐Controlled Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Mycophenolate mofetil (MMF) is an immunosuppressive drug widely used by solid organ transplant recipients. Although it is known that MMF suppresses immune responses, its exact effects on specific vaccinations have not been investigated yet. Mucosal vaccinations are increasingly used, such as a cholera vaccination consisting of two oral immunizations ...
Boukje C. Eveleens Maarse, Aliede E. in 't Veld, Hendrika W. Grievink, Manon A.A. Jansen, Matthijs Moerland   +4 more
wiley   +1 more source

Nocturnal asthma [PDF]

, 1991
Remien, J., Liebl, B., Haen, E., Fruhmann, G., Schopohl, J., Hauck, R., Emslander, H.-P., Langenmayer, Irmgard   +7 more
core   +1 more source

CytoScan: Automated Detection of Technical Anomalies for Cytometry Quality Control

Cytometry Part A, EarlyView.
ABSTRACT Studies evaluating cellular phenotypes by cytometry techniques are increasingly facing analytical challenges due to the multitudes of samples and parameters that are evaluated concurrently. Spurious technical effects resulting from a lack of standardization can affect marker distributions and further complicate multi‐sample analyses.
Tim R. Mocking, Felix Zwolle, Yejin Park, Angèle Kelder, Yvan Saeys, Jacqueline Cloos, Sofie van Gassen, Costa Bachas   +7 more
wiley   +1 more source

High‐Dimensional Spectral Flow Cytometry Panel for Immunophenotypic Characterization of Fixed Whole Blood Samples

Cytometry Part A, EarlyView.
ABSTRACT Peripheral blood mononuclear cells (PBMCs) are commonly used for immune profiling in clinical research, but their isolation and cryopreservation present logistical challenges, particularly in settings with limited access to research facilities. To address this, we implemented a whole blood fixation protocol to preserve surface protein epitopes
Vaishnavi Parthasarathy, Alexander T. Heubeck, Tyanna Stuckey, Veronica Hernandez, Blessing Musgrove, Maia M. Bennett‐Boehm, Troy Torgerson, Peter Skene, Julian Reading   +8 more
wiley   +1 more source