Results 21 to 30 of about 221,944 (307)

TGF-β is elevated in hyperuricemic individuals and mediates urate-induced hyperinflammatory phenotype in human mononuclear cells

Arthritis Research & Therapy, 2023
Background Soluble urate leads to a pro-inflammatory phenotype in human monocytes characterized by increased production of IL-1β and downregulation of IL-1 receptor antagonist, the mechanism of which remains to be fully elucidated.
Viola Klück, Georgiana Cabău, Linda Mies, Femke Bukkems, Liesbeth van Emst, René Bakker, Arjan van Caam, HINT consortium, Tania O. Crişan, Leo A. B. Joosten   +9 more
doaj   +1 more source

DNA Methylation Profile in Human Cord Blood Mononuclear Leukocytes From Term Neonates: Effects of Histological Chorioamnionitis

Frontiers in Pediatrics, 2020
Background: Histological chorioamnionitis (HCA) is an infection/inflammation of fetal membranes and complicates 5.2–28.5% of all live births. Exposure to HCA can have long-term consequences including abnormal neurodevelopment and an increased risk for ...
Gina Fong, Suhita Gayen nee' Betal, Swati Murthy, Michael Favara, Joanna S. Y. Chan, Sankar Addya, Thomas H. Shaffer, Jay Greenspan, Vineet Bhandari, Dongmei Li, Irfan Rahman, Zubair H. Aghai   +11 more
doaj   +1 more source

Histological assessment of the efficiency of rabbit serum in healing skin wounds [PDF]

Veterinary World, 2019
Aim: This study aimed to investigate the impact of rabbit serum on skin wound healing with the help of histological examination. Materials and Methods: A total of ten indigenous rabbits were used in this study. The animals were divided into two groups:
Abeer Ahmed Majeed, Dhyaa Ab. Abood
doaj   +1 more source

Changes in the activity of lysosomal cysteine proteases of plasma mononuclear and polymorphonuclear blood leukocytes in Alzheimer’s disease

Бюллетень сибирской медицины, 2020
Aim. To study the level of activity of lysosomal cysteine proteases (cathepsins H, B, L) in blood plasma and fractionated leukocytes (polymorphonuclear and mononuclear) in patients with Alzheimer’s disease in comparison with similar indicators in persons
M. G. Sorokina, M. A. Fomina, D. S. Petrov, N. V. Korotkova   +3 more
doaj   +1 more source

Cytokine Profile in Human Peripheral Blood Mononuclear Leukocytes Exposed to Immunoadjuvant and Adjuvant-Free Vaccines Against Influenza

Frontiers in Immunology, 2020
Background: In the last decade, adjuvant-containing vaccines, exerting different effects on the immune system, including the production of cytokines, which are one of the most important regulatory systems of the body, are introduced into practice ...
Mikhail Petrovich Kostinov, Mikhail Petrovich Kostinov, Nelli Kimovna Akhmatova, Ekaterina Alexandrovna Khromova, Aristitsa Mikhailovna Kostinova   +4 more
doaj   +1 more source

The Effect of Intracellular Tacrolimus Exposure on Calcineurin Inhibition in Immediate- and Extended-Release Tacrolimus Formulations

Pharmaceutics, 2023
Despite intensive monitoring of whole blood tacrolimus concentrations, acute rejection after kidney transplantation occurs during tacrolimus therapy.
Pere Fontova, Lisanne N. van Merendonk, Anna Vidal-Alabró, Raül Rigo-Bonnin, Gema Cerezo, Stefaan van Oevelen, Oriol Bestard, Edoardo Melilli, Nuria Montero, Ana Coloma, Anna Manonelles, Joan Torras, Josep M. Cruzado, Josep M. Grinyó, Helena Colom, Nuria Lloberas   +15 more
doaj   +1 more source

The Inositol- 1,4,5=Trisphosphate System Is Involved in Rapid Effects of Aldosterone in Human Mononuclear Leukocytes [PDF]

, 1993
There is increasing evidence for rapid steroid action on electrolyte transport in human mononuclear leukocytes (HML). In HML, aldosterone stimulates the Na+/H+ antiporter within a few minutes. Because a variety of hormones and growth factors activate the
Wehling, Martin, Theisen, Karl, Eisen, Christoph, Aktas, Janet, Christ, Michael, M. Christ   +5 more
core   +1 more source

Anti-inflammatory effect of the flavonoid fraction of Lepechinia meyenii (Walp.) Epling (Sage) on leukocytes of patients with rheumatoid arthritis

Revista Peruana de Medicina Experimental y Salud Pública, 2018
Objectives. to assess the anti-inflammatory effect of the flavonoid fraction of Lepechinia meyenii (Walp.) Epling on leukocytes of patients with rheumatoid arthritis (RA). Materials and Methods.
Carlos Alberto Arenas-Chavez, Tomas Wiche-Salinas, Ignacio Valencia-Mercado, Ronald Calle-Valdez, Corina Vera-Gonzales, Stephanie Malaga-Contreras, Fernando Flores-Rivera, Carlos Huanqui-Guerra   +7 more
doaj   +1 more source

Mononuclear Leukocyte Mineralocorticoid Receptors [PDF]

Hypertension, 2006
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Armanini, Decio, Fiore, Cristina, Calò, Lorenzo A   +2 more
openaire   +2 more sources

Nongenomic effects of aldosterone on phosphocreatine levels in human calf muscle during recovery from exercise. [PDF]

, 1996
Nongenomic in vitro effects of aldosterone on the sodium-proton antiport and intracellular second messengers have been described in human mononuclear leukocytes, vascular smooth muscle cells, and endothelial cells.
Wehling, Martin, Zange, Jochen, Sippel, Katrin, Gerzer, R., Wehling, M., Zange, G., Müller, Klaus, Müller, K., Gerzer, Rupert, Wehling, M. (1), Mueller, K.   +10 more
core   +1 more source