Results 201 to 210 of about 80,122 (309)

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Platelet-specific P2Y₁ receptor deficient mice have suppressed pulmonary leukocyte recruitment in response to lipopolysaccharide. [PDF]

Respir Res
Pan D, Lino-Alvarado A, Amison RT, Oralman T, Evans R, Baker O, Cocks G, Page CP, Pitchford SC.   +8 more
europepmc   +1 more source

Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo, Adriana M. de Oliveira, Nobuhiko Kamada, Sho Kitamoto   +3 more
wiley   +1 more source

Immunohistochemical Characterization of the Immune Response in Chronic Endometritis Caused by <i>Chlamydia trachomatis</i>. [PDF]

Diagnostics (Basel)
Miranda-Maldonado I, Gopar-Cuevas Y, Álvarez-Cuevas S, Gallegos-Avila G, Ancer-Rodríguez J, Ortega-Martínez M, Jaramillo-Rangel G.   +6 more
europepmc   +1 more source

Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship

Journal of Periodontal Research, EarlyView.
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw, Ren Jie Jacob Chew, Charlene Enhui Goh, Ali A. Abdulkareem, Dana T. Graves   +4 more
wiley   +1 more source

Pathological insights of human CD34+ hematopoietic stem cell-engrafted NSG mice: Implications for the safety assessment of cancer immunotherapy drugs. [PDF]

Vet Pathol
Giusti AM, Sam J, Colombetti S, Veiga IB, Monné Rodríguez JM.   +4 more
europepmc   +1 more source

Viruses, Periodontitis, and Systemic Diseases

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the viral involvement in periodontitis and its relevance for systemic diseases. The oral cavity acts as an active viral reservoir and dissemination platform, where virus–microbiome interactions may promote dysbiosis, periodontitis progression, and systemic inflammatory effects, while the ...
K. N. Stolte, Y. L. Hernandez‐Kapila, H. Dommisch   +2 more
wiley   +1 more source

Diabetes exacerbates destructive inflammation by activating the CD137L-CD137 axis in dendritic and IL-17+ T cells. [PDF]

J Clin Invest
Huang X, Liu M, Gonzalez MV, Debnath R, Afzali H, Choi Y, Kim SA, Ko KI, Graves DT.   +8 more
europepmc   +1 more source

Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases

Obesity Reviews, EarlyView.
ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar, Joanna Razafiarison, Fawaz Alzaid, Fahd Al‐Mulla, Rasheed Ahmad   +4 more
wiley   +1 more source

Modulation of Master Transcription Factor Expression of Nile Tilapia Leukocytes via Cholinergic Pathways. [PDF]

Int J Mol Sci
Girón-Pérez MI, Ramírez-Ibarra KM, Covantes-Rosales CE, Girón-Pérez DA, Razura-Carmona FF, Contis-Montes de Oca A, Morales-Montor J, Pavón L, Toledo-Ibarra GA.   +8 more
europepmc   +1 more source