Results 141 to 150 of about 594,733 (360)
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth+2 more
wiley +1 more source
Lanthanide ytterbium ions are introduced into Bi2WO6 nanosheets to boost ROS generation under US stimulation. These ytterbium‐doped Bi2WO6 nanosheets serve as efficient sonosensitizers, enabling broad‐spectrum bacterial eradication. To improve biocompatibility for in vivo sonodynamic therapy, the sonosensitizers are integrated into hydrogel matrix ...
Xinyue Lao+6 more
wiley +1 more source
Studies on the Fibrinogen, Dextran and Phytohemagglutinin Methods of Isolating Leukocytes [PDF]
William A. Skoog, William S. Beck
openalex +1 more source
To investigate the mechanisms about the enhanced buffering effect and morphological retention in fully lithiated Sn–Bi alloys, this study introduces a new bulk bimetallic Sn–Bi alloy with fine grains of uniformly distributed Sn and Bi alloys (≈50 nm) via cooling rate control. This design effectively relieves internal energy buildup and suppresses crack
Hyeon Seo Park+6 more
wiley +1 more source
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche+16 more
wiley +1 more source
Elevated basophil count is associated with increased odds of endometriosis
Immunological dysregulation plays a fundamental role in the inflammatory aspects of endometriosis. Circulating blood leukocytes, one of the most abundant immune cell populations in the human body, have been shown diagnostic significance in some diseases.
Qian Feng+9 more
doaj +1 more source
THE ROLE OF POLYMORPHONUCLEAR LEUKOCYTES IN THE INITIATION AND CESSATION OF THE ARTHUS VASCULITIS [PDF]
Charles G. Cochrane+2 more
openalex +1 more source
In a murine model of acute lung injury, pulmonary administration of lipid nanoparticles carrying TNFα siRNA enables targeted delivery to immune cells. The study emphasises the importance of optimizing LNP distribution and delivery timing to improve therapeutic outcomes and develop emergency therapies for lung hyperinflammation.
Qinglin Wang+14 more
wiley +1 more source
A METHOD FOR THE RAPID SEPARATION OF LEUKOCYTES AND NUCLEATED ERYTHROCYTES FROM BLOOD OR MARROW WITH A PHYTOHEMAGGLUTININ FROM RED BEANS (PHASEOLUS VULGARIS) [PDF]
Jonah G. Li, Edwin E. Osgood
openalex +1 more source
A novel dissolving microneedle platform preserves HPV virus‐like particle (VLP) immunogenicity by maintaining structural integrity, crucial for eliciting potent immune responses. Buccal administration induces robust immune response, high neutralizing antibody titers, and durable sterile protection across oral and vaginal mucosal sites.
Hyemi Kim+12 more
wiley +1 more source