Gene expression of chemokines CX3CL1 and CXCL16 and their receptors, CX3CR1 and CXCR6, in peripheral blood mononuclear cells of patients with relapsing-remitting multiple sclerosis - a pilot study [PDF]
Background/Aim. In vitro and in vivo studies show that CX3CL1 and CXCL16 chemokines and their specific receptors, CX3CR1 and CXCR6, respectively, mediate mechanism of neuroinflammation during the pathogenesis of multiple sclerosis (MS).
Stojković Ljiljana +5 more
doaj +1 more source
Aim. To study the predictors of adverse events in hypertensive (HTN) patients, including those with chronic respiratory diseases (CRDs).Material and methods.
M. I. Smirnova +5 more
doaj +1 more source
Quick Leukocyte Nucleus Segmentation in Leukocyte Counting [PDF]
The leukocyte nucleus quick segmentation is one of the key techniques in leukocyte real-time online scanning of human blood smear. We propose a quick leukocyte nucleus segmentation method based on the component difference in RGB color space. By analyzing the captured microscopic images of the peripheral blood smears from the autoscanning microscope, it
Yapin Wang, Yiping Cao
openaire +2 more sources
High level of RNA HAS2-AS1 in the buffy coat of a patient blood sample is a more informative prognostic marker of COVID-19 clinical course compared to the level of hyaluronic acid in plasma [PDF]
Numerous studies have confirmed the association of COVID-19 clinical course with the blood levels of hyaluronic acid and long non-coding RNA HAS2-AS1 as a positive regulator of hyaluronan synthase.
E. Dubrovskyi +3 more
doaj +1 more source
Leukocytes in type 1 diabetes mellitus: the changes they undergo and induce
As leukocytes represent cellular and humoral immunity at the same time, they are a vital part of every immune process. This also stands for autoimmune processes and disorders, such as diabetes, specifically type 1 diabetes mellitus.
О. М. Kuchurka +4 more
doaj +1 more source
Background. Diabetes mellitus intensifies non-enzymatic glycosylation (glycation) of biomolecules under conditions of chronic hyperglycemia and facilitates accumulation of advanced glycation end products.
Kh. Ye. Furtak +2 more
doaj +1 more source
Phenotyping of Leukocytes and Leukocyte-Derived Extracellular Vesicles [PDF]
Extracellular vesicles (EVs) have a demonstrated involvement in modulating the immune system. It has been proposed that EVs could be used as biomarkers for detection of inflammatory and immunological disorders. Consequently, it is of great interest to investigate EVs in more detail with focus on immunological markers.
Pugholm, Lotte Hatting +5 more
openaire +4 more sources
Modulation by luminal factors on the functions and migration of intestinal innate immunity
Luminal antigens, nutrients, metabolites from commensal bacteria, bile acids, or neuropeptides influence the function and trafficking of immune cells in the intestine.
Masaaki Higashiyama +2 more
doaj +1 more source
CD203c is expressed by human fetal hepatoblasts and distinguishes subsets of hepatoblastoma
Background & AimsHepatocytic cells found during prenatal development have unique features compared to their adult counterparts, and are believed to be the precursors of pediatric hepatoblastoma.
Marcus O. Muench +13 more
doaj +1 more source
Recently, there have been increasing an interest to study a role of polyamines in intercellular interactions, especially in the focus of inflammation, where accumulation of such polycations is observed.
Anatoliy P. Godovalov +2 more
doaj +1 more source

