Results 221 to 230 of about 594,733 (360)

Reprogramming of Fatty Acid Metabolism via PPARα‐Orchestrated FADS2 in Keratinocytes Modulates Skin Inflammation in Psoriasis

open access: yesAdvanced Science, EarlyView.
This study identifies fatty acid desaturase 2 (FADS2) as a key regulator linking polyunsaturated fatty acid (PUFA) metabolism to psoriatic inflammation. FADS2 deficiency impairs docosahexaenoic acid (DHA) biosynthesis, enhances NF‐κB signaling, and promotes neutrophil‐driven skin inflammation. PPARα transcriptionally activates FADS2, and its activation
Jiangluyi Cai   +19 more
wiley   +1 more source

Artificial intelligence-driven label-free detection of chronic myeloid leukemia cells using ghost cytometry. [PDF]

open access: yesSci Rep
Suzuki K   +13 more
europepmc   +1 more source

Microphysiological Uremia Model Reveals Biophysical Potentiators of Vascular Dysfunction

open access: yesAdvanced Science, EarlyView.
A microfluidic platform of engineered blood vessels is developed to study the role of mechanical forces in immune cell adhesion and extravasation in uremic microenvironments. Elevated pressure increases monocyte activity, with ICAM‐1 as a key driver. Matrix density influences monocyte phenotypes, but the uremic environment consistently promoted a pro ...
Mitesh Rathod   +9 more
wiley   +1 more source

Correlation of the differential expressions of RANK, RANKL, and OPG with obesity in the elderly population in Xinjiang. [PDF]

open access: yesOpen Med (Wars)
Liu J   +8 more
europepmc   +1 more source

Defective Leukocyte Metabolism

open access: yesNew England Journal of Medicine, 1979
Lew, Daniel Pablo   +4 more
openaire   +4 more sources

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