Results 241 to 250 of about 594,733 (360)

Lifespan‐Regulated CAR‐Macrophages from Myeloid Progenitors for Enhanced Colorectal Cancer Therapy

Advanced Science, EarlyView.
Using a tamoxifen‐inducible Hoxb8 system, proliferative bone marrow progenitors can be generated, which are subsequently engineered with an anti‐CEA CAR construct containing a suicide gene (iCas9) and differentiated into CAR‐macrophages. This method facilitates scale up the production of CAR‐macrophages.
Chuancheng Gao, Fangling Hong, Yao Dong, Yong Fu, Yunong Ma, Xuedi Sun, Junfeng Zhang, Jiangning Chen, Zhen Huang   +8 more
wiley   +1 more source

Improved leukocyte classification in bone marrow cytology using convolutional neural network with contrast enhancement. [PDF]

Sci Rep
Mehmood S, Shahzad T, Zubair M, Khan FM, Khan MA, Ouahada K, Gandomi AH.   +6 more
europepmc   +1 more source

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

Advanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang, Lixia Song, Rui Fan, Qianqian Chen, Ruisheng Fu, Mei You, Yuxiao Wu, Meng Cai, Yong Li, Meihong Xu   +9 more
wiley   +1 more source

Donor liver natural killer cells ameliorate liver allograft rejection via inducing apoptosis of alloreactive CD8⁺ T cells generating CD4⁺CD25⁺ regulatory T cells. [PDF]

Sci Rep
Yu J, Wu J, Long T, Lv L, Chen Z, Lin Z, Zhu H, Li G, Wan Y.   +8 more
europepmc   +1 more source

Novel Antimicrobial Protein Fibroblast Growth Factor 8 Accelerates Skin Wound Healing via Directly Inhibiting Bacteria and Activating Glycolysis

Advanced Science, EarlyView.
Wound infections induce gcFGF8a expression, which subsequently executes direct antimicrobial activity to suppress local infection while simultaneously activating the FGFR4‐mediated ERK/AKT‐mTOR signaling cascade, thereby upregulating HIF1α and enhancing glycolysis. These coordinated actions synergistically promote tissue repair by eliminating pathogens
Ya‐Zhen Hu, Ting Wang, Chang‐Song Wu, Jie Wang, Xue‐Qing Han, Yong‐An Zhang, Xu‐Jie Zhang   +6 more
wiley   +1 more source

Functional Characterization of <i>TNFα</i> in the Starry Flounder (<i>Platichthys stellatus</i>) and Its Potential as an Immunostimulant. [PDF]

Animals (Basel)
Sohn MY, Kang G, Kim KH, Son HJ, Park CI.   +4 more
europepmc   +1 more source

Studies on the Wandering Leukocytes on the Various Mucosae in Human Subjects and Animals.

, 1952
Fusao Morita
openalex   +2 more sources

Bionic Microneedle Patch Inspired by Drosophila Tarsal Paws Boosts Healing in Bacterial Infectious Stomatitis

Advanced Science, EarlyView.
Microneedle suction cup patches, prepared using bionic Drosophila tarsal claws, can effectively treat bacterial infectious stomatitis by rapidly and efficiently leveraging multiple effects, including antibacterial and anti‐inflammatory properties, promotion of vasodilation, and active mechanical contraction of the wound.
Jiaqi Qin, Cewen Hu, Xiaohong Ran, Huajing Zeng, Jie Zhang, Bin Liu, Zengjie Fan   +6 more
wiley   +1 more source

Exploratory Study of CD10^low Polymorphonuclear Leukocytes Preceding and Correlating With Postsurgical Inflammation. [PDF]

Scand J Immunol
Westermann TM, Sendas J, Koller AS, Jovanovski D, Hüsken D, Lessing PML, Weber B, Mühling B, Liebold A, Messerer DAC, Huber-Lang M, Wohlgemuth L.   +11 more
europepmc   +1 more source

Studies on the Effect of Adrenalin, Cortisone and ACTH on the White Blood Cell especially on the Eosinophilic Leukocyte by the Tissue Culture of the Bone Marrow-mainly on the mechanism of eosinopenia

, 1956
Shinrô Yamamoto
openalex   +2 more sources