Results 111 to 120 of about 711,937 (246)

Effectiveness of Immune Checkpoint Inhibitors in Transplant Recipients with Progressive Multifocal Leukoencephalopathy

Emerging Infectious Diseases, 2019
Antibodies against PD1 have been used to treat progressive multifocal leukoencephalopathy (PML), a rare brain disease caused by JC virus. We used these antibodies (nivolumab) to treat PML in 3 kidney transplant recipients.
Chloé Médrano, F. Vergez, C. Mengelle, S. Faguer, N. Kamar, A. Del Bello   +5 more
semanticscholar   +1 more source

Immunology of progressive multifocal leukoencephalopathy [PDF]

, 2021
The high prevalence of asymptomatic JC polyomavirus (JCV) infection in the general population indicates coexistence with the human host and efficient immune control in healthy individuals.
Jelcic, Ilijas, Martin, Roland, Faigle, Wolfgang, Jelcic, Ivan, Sospedra, Mireia   +4 more
core  

Progressive Multifocal Leukoencephalopathy: Current Insights

Degenerative Neurological and Neuromuscular Disease, 2019
Cases of PML should be evaluated according to predisposing factors, as these subgroups differ by incidence rate, clinical course, and prognosis. The three most significant groups at risk of PML are patients with hematological malignancies mostly ...
Marge Kartau, J. Sipilä, E. Auvinen, Maarit Palomäki, A. Verkkoniemi-Ahola   +4 more
semanticscholar   +1 more source

Progressive multifocal leukoencephalopathy in HIV with atypical presentation and prognostic outcome causing diagnostic dilemma: a case report [PDF]

Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease caused by John Cunningham virus (JCV) that affects immunocompromised individuals, particularly human immunodeficiency virus (HIV)-positive.
Wan Ahmad Kammal, Wan Syahira Ellani, Petrick Periyasamy, Abd Halim, Haizlene, Nur Nadhirah Mesran, Md Yasin, Mazapuspavina, Nadhirah Mesran, Nur, Abdul-Razak, Suraya, Wan Syahira Ellani Wan Ahmad Kammal, Suraya Abdul-Razak, Mazapuspavina Md Yasin, Haizlene Abd Halim, Periyasamy, Petrick   +11 more
core   +1 more source

Visual consequences of medications for multiple sclerosis: the good, the bad, the ugly, and the unknown

Eye and Brain, 2017
Heather E Moss1,2 1Department of Ophthalmology, Stanford University, Palo Alto, CA, USA; 2Department of Neurology & Neuroscience, Stanford University, Stanford, CA, USA Abstract: Multiple sclerosis (MS) is associated with vision changes both due to ...
Moss HE
doaj  

PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY AFTER ORTHOTOPIC LIVER TRANSPLANTATION: A SYSTEMATIC REVIEW

Background Progressive multifocal leukoencephalopathy is a demyelinating disease of the nervous system. It is caused by reactivation of the John Cunningham Virus in patients with compromised immune systems.
Katarzyna Mania, Julia Bąk, Wojciech Frączyk, Agata Świątek, Bartosz Machnio, Agnieszka Stankowska, Mateusz Krysiak, Bogna Błachowska, Natalia Jasińska, Kamil Andruszkiewicz, Natalia Turzyńska   +10 more
core   +1 more source

Treatment of progressive multifocal leukoencephalopathy with interleukin 7

, 2014
IMPORTANCE: No reliable treatment options are known for progressive multifocal leukoencephalopathy with underlying immunodeficiency. We describe successful compassionate use of recombinant human interleukin 7 in a patient with idiopathic CD4+ T-cell ...
Hirsch, Hans H., Leboeuf, Céline, Croughs, Thérèse, Rinaldo, Christine Hanssen, Sereti, Irini, Alstadhaug, Karl B., Henriksen, Stian   +6 more
core   +1 more source

Posterior fossa tremor induced by HIV-associated progressive multifocal leukoencephalopathy [PDF]

, 2005
Sporer, B., B. Sporer, K. Seelos, H.-W. Pfister, F. Asmus, Seelos, Klaus, Bötzel, Kai, K. Boetzel, Asmus, F., Pfister, H. W.   +9 more
core   +1 more source

A rare case of progressive multifocal leukoencephalopathy

Radiology Case Reports
Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease of the central nervous system (CNS) due to John Cunningham (JC) virus reactivation most often in immunocompromised patients.
Jayanthraj Gone, DO, Tyler Fontaine, DO, Gaurav Kumar, MD   +2 more
doaj   +1 more source

Progressive Multifocal Leukoencephalopathy: Endemic Viruses and Lethal Brain Disease

, 2017
In 1971, the first human polyomavirus was isolated from the brain of a patient who died from a rapidly progressing demyelinating disease known as progressive multifocal leukoencephalopathy. The virus was named JC virus after the initials of the patient.
Sheila A. Haley, Walter J. Atwood
core   +1 more source