Results 91 to 100 of about 711,937 (246)
Diagnosis of progressive multifocal leukoencephalopathy is usually based on the clinical presentation, on the demonstration of the brain lesions at the magnetic resonance imaging examination, and on the detection of the JC virus DNA in the cerebrospinal ...
Guglielmo Manenti +7 more
doaj +1 more source
Background Progressive multifocal leukoencephalopathy (PML) is one of the most serious treatment-related complications that is encountered in patients with multiple sclerosis (MS).
Salman Mansoor +6 more
doaj +1 more source
Inflammatory Bowel Disease: Mechanisms and Therapeutic Advances
Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, is a rising, multifactorial chronic disorder driven by dysregulated mucosal immunity in genetically susceptible individuals and influenced by environmental and microbial factors.
Andrea Papait +5 more
wiley +1 more source
Childhood case of progressive multifocal leukoencephalopathy with improved clinical outcome
A 6-year-old boy who hall been in remission from acute lymphoblastic leukemia for 2.5 years presented with seizures, hemiparesis, visual loss, and white- and gray-matter lesions oil cranial magnetic resonance imaging.
Yalaz, K +5 more
core +1 more source
PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY: A CASE REPORT
Progressive Multifocal Leukoencephalopathy (PML) is a demyelinating disease that severely affects the central nervous system (CNS) through the JC polyomavirus.
Bruna Kochhann Menezes +4 more
doaj +1 more source
ABSTRACT Background Glatiramer acetate is an injectable disease‐modifying therapy indicated for multiple sclerosis (MS). Aim To evaluate the real‐world safety and effectiveness of glatiramer acetate for MS in Japan. Methods A prospective, multicenter, observational, all‐case post‐marketing survey was conducted in Japan between November 2015 and March ...
Masaaki Niino +3 more
wiley +1 more source
Infection risk in rheumatoid arthritis patients treated with biologic and targeted therapies
In this context, infections associated with each biologic and targeted drug are summarized to inform the stratification of RA patients, including the characteristics of the susceptible patients and their concomitant therapy. We aim to provide a benefit‐risk analysis for clinical decision, and vital indications for the prevention of highly correlated ...
Lujing Wang, Jieshi Lin, Jie Qian
wiley +1 more source
Targeting progressive multiple sclerosis: Toward mechanism‐informed precision medicine
Abstract Multiple sclerosis has undergone a therapeutic revolution over the past three decades. Randomized clinical trials and real‐world data demonstrate that modern disease‐modifying therapies substantially reduce relapse rates and acute inflammatory activity detected by magnetic resonance imaging (MRI).
Fredrik Piehl +3 more
wiley +1 more source
Progressive multifocal leukoencephalopathy
Objective To characterize the risk factors, clinical course, and treatment of patients with progressive multifocal leukoencephalopathy (PML) diagnosed and followed over a 25-year epoch at 2 academic hospitals.
Pria Anand +4 more
semanticscholar +1 more source
HIV-Associated Progressive Multifocal Leukoencephalopathy: A Case Study
Progressive multifocal leukoencephalopathy (PML) is a rare, life-threatening, infectious, lytic, demyelinating disease that results from reactivation of the virulent JC polyomavirus (JCV) “major opportunistic infection” in immunosuppressed individuals ...
Elsayed Abed +10 more
doaj +2 more sources

