Results 91 to 100 of about 711,937 (246)

Early Magnetic Resonance Detection of Natalizumab-Related Progressive Multifocal Leukoencephalopathy in a Patient with Multiple Sclerosis

open access: yesCase Reports in Radiology, 2013
Diagnosis of progressive multifocal leukoencephalopathy is usually based on the clinical presentation, on the demonstration of the brain lesions at the magnetic resonance imaging examination, and on the detection of the JC virus DNA in the cerebrospinal ...
Guglielmo Manenti   +7 more
doaj   +1 more source

Natalizumab-associated progressive multifocal leukoencephalopathy (PML) in multiple sclerosis (MS): “a case report from Ireland with review of literature, clinical pitfalls and future direction”

open access: yesThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2021
Background Progressive multifocal leukoencephalopathy (PML) is one of the most serious treatment-related complications that is encountered in patients with multiple sclerosis (MS).
Salman Mansoor   +6 more
doaj   +1 more source

Inflammatory Bowel Disease: Mechanisms and Therapeutic Advances

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, is a rising, multifactorial chronic disorder driven by dysregulated mucosal immunity in genetically susceptible individuals and influenced by environmental and microbial factors.
Andrea Papait   +5 more
wiley   +1 more source

Childhood case of progressive multifocal leukoencephalopathy with improved clinical outcome

open access: yes, 2005
A 6-year-old boy who hall been in remission from acute lymphoblastic leukemia for 2.5 years presented with seizures, hemiparesis, visual loss, and white- and gray-matter lesions oil cranial magnetic resonance imaging.
Yalaz, K   +5 more
core   +1 more source

PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY: A CASE REPORT

open access: yesBrazilian Journal of Infectious Diseases
Progressive Multifocal Leukoencephalopathy (PML) is a demyelinating disease that severely affects the central nervous system (CNS) through the JC polyomavirus.
Bruna Kochhann Menezes   +4 more
doaj   +1 more source

Real‐World Safety and Effectiveness of Glatiramer Acetate in Patients With Multiple Sclerosis: Final Results of Post‐Marketing Surveillance in Japan

open access: yesNeurology and Clinical Neuroscience, Volume 14, Issue 5, Page 386-397, September 2026.
ABSTRACT Background Glatiramer acetate is an injectable disease‐modifying therapy indicated for multiple sclerosis (MS). Aim To evaluate the real‐world safety and effectiveness of glatiramer acetate for MS in Japan. Methods A prospective, multicenter, observational, all‐case post‐marketing survey was conducted in Japan between November 2015 and March ...
Masaaki Niino   +3 more
wiley   +1 more source

Infection risk in rheumatoid arthritis patients treated with biologic and targeted therapies

open access: yesRheumatology &Autoimmunity, Volume 6, Issue 3, Page 149-159, September 2026.
In this context, infections associated with each biologic and targeted drug are summarized to inform the stratification of RA patients, including the characteristics of the susceptible patients and their concomitant therapy. We aim to provide a benefit‐risk analysis for clinical decision, and vital indications for the prevention of highly correlated ...
Lujing Wang, Jieshi Lin, Jie Qian
wiley   +1 more source

Targeting progressive multiple sclerosis: Toward mechanism‐informed precision medicine

open access: yesJournal of Internal Medicine, Volume 300, Issue 3, Page 238-257, September 2026.
Abstract Multiple sclerosis has undergone a therapeutic revolution over the past three decades. Randomized clinical trials and real‐world data demonstrate that modern disease‐modifying therapies substantially reduce relapse rates and acute inflammatory activity detected by magnetic resonance imaging (MRI).
Fredrik Piehl   +3 more
wiley   +1 more source

Progressive multifocal leukoencephalopathy

open access: yesNeurology: Neuroimmunology & Neuroinflammation, 2019
Objective To characterize the risk factors, clinical course, and treatment of patients with progressive multifocal leukoencephalopathy (PML) diagnosed and followed over a 25-year epoch at 2 academic hospitals.
Pria Anand   +4 more
semanticscholar   +1 more source

HIV-Associated Progressive Multifocal Leukoencephalopathy: A Case Study

open access: yesActa Medica Indonesiana, 2023
Progressive multifocal leukoencephalopathy (PML) is a rare, life-threatening, infectious, lytic, demyelinating disease that results from reactivation of the virulent JC polyomavirus (JCV) “major opportunistic infection” in immunosuppressed individuals ...
Elsayed Abed   +10 more
doaj   +2 more sources

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