Results 71 to 80 of about 12,469 (206)

Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy

, 2006
Background: Progressive multifocal leukoencephalopathy (PML) was reported to have developed in three patients treated with natalizumab. We conducted an evaluation to determine whether PML had developed in any other treated patients.
Major, E.O., Clifford, D.B., Habil, M., Fischer, S., Barkhof, F., Yousry, T.A., Hou, J., Radue, E.-W., Ryschkewitsch, C., Mueller-Lenke, N., Jäger, H.R., Sanchez, E., Curfman, B., Miszkiel, K., Fahle, G.   +14 more
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Neurological Complications After Pediatric Liver and Kidney Transplantation: A Comprehensive Review of Acute Symptomatic Seizures

Pediatric Transplantation, Volume 30, Issue 5, May 2026.
ABSTRACT Acute symptomatic seizures (ASS) represent one of the most frequent and clinically significant neurological complications following pediatric liver and kidney transplantation. Despite their clinical relevance, available evidence remains fragmented; pediatric‐specific data are limited, and no standardized diagnostic or management framework has ...
Konstantin Semash, Timur Dzhanbekov, Mansur Nasirov, Bakhtiyorjon Umarov, Navruz Qambarov, Bakhtiyor Khamdamov   +5 more
wiley   +1 more source

Progressive multifocal leukoencephalopathy in HIV with atypical presentation and prognostic outcome causing diagnostic dilemma: a case report [PDF]

Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease caused by John Cunningham virus (JCV) that affects immunocompromised individuals, particularly human immunodeficiency virus (HIV)-positive.
Wan Ahmad Kammal, Wan Syahira Ellani, Petrick Periyasamy, Abd Halim, Haizlene, Nur Nadhirah Mesran, Md Yasin, Mazapuspavina, Nadhirah Mesran, Nur, Abdul-Razak, Suraya, Wan Syahira Ellani Wan Ahmad Kammal, Suraya Abdul-Razak, Mazapuspavina Md Yasin, Haizlene Abd Halim, Periyasamy, Petrick   +11 more
core   +1 more source

An Accurate Genetic Colocalisation Method for the HLA Locus

HLA, Volume 107, Issue 5, May 2026.
ABSTRACT Genetic colocalisation analyses are frequently conducted to determine if causal signals at a genetic locus are shared between two phenotypes. However, colocalisation is rarely undertaken at the HLA locus, due to its complex linkage disequilibrium (LD) and high polymorphism density.
Guillaume Butler‐Laporte, Tianyuan Lu, Sam Morris, Wenmin Zhang, Gavin Band, Fergus Hamilton, Amanda Chong, Kuang Lin, Ruth Nanjala, J. Brent Richards, Mei‐Hsuan Lee, Ling Yang, Pang Yao, Liming Li, Zhengming Chen, Yang Luo, Iona Y. Millwood, Robin G. Walters, Alexander J. Mentzer   +18 more
wiley   +1 more source

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

Transfusion, EarlyView.
Thane Kubik, Theodros Mamo, David H. McKenna   +2 more
wiley   +1 more source

Dynamics of complete responses (CRs) in patients with relapsed or refractory follicular lymphoma (R/R FL) treated with odronextamab in the ELM‐2 study

HemaSphere, Volume 10, Issue 4, April 2026.
Abstract Complete response (CR) is an important treatment goal in follicular lymphoma (FL). In relapsed or refractory (R/R) FL, CR rates decline, and disease progression accelerates with each treatment line, with particularly poor outcomes in patients with high‐risk features.
Stefano Luminari, Ana Jiménez‐Ubieto, Geoffrey Chong, David Tucker, Srikanth Ambati, Chinjune Lin, Hesham Mohamed, Jurriaan Brouwer‐Visser, Chetachi Akunna Otele, Giovanni Antico, Jose C. Villasboas   +10 more
wiley   +1 more source

Progressive multifocal leukoencephalopathy - Epidemiology, immune response, clinical differences, treatment

, 2019
Progressive multifocal leukoencephalopathy (PML) is a severe disease of the central nervous system with very high mortality. It is caused by the JC virus with high seroprevalence, at up to 80%.
Havlíčková, Kateřina, Husa, Petr, Snopková, Svatava, Volfová, Pavlína, Svačinka, Radek, Fašaneková, Lenka, Mihalčin, Matúš, Štourač, Petr, Snopek, Petr   +8 more
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HIV-Associated Progressive Multifocal Leukoencephalopathy: A Case Study

Acta Medica Indonesiana, 2023
Progressive multifocal leukoencephalopathy (PML) is a rare, life-threatening, infectious, lytic, demyelinating disease that results from reactivation of the virulent JC polyomavirus (JCV) “major opportunistic infection” in immunosuppressed individuals ...
Elsayed Abed, Ahmed Farag El-adawey, Mohamed Hamed Rashad, Ahmed Essmat, Mohammed Ali, Ahmed Hassan Elsheshiny, Abdel-Ghaffar Fayed, Fathy Elbaz, Mahmoud Galal Ahmed, Zohreh Abna, Shaimaa Sayed Khater   +10 more
doaj   +2 more sources

A case of developing progressive multifocal leukoencephalopathy while using rituximab and mycophenolate mofetil in refractory systemic lupus erythematosus

, 2018
Yuichi Ishikawa, Tadamichi Kasuya, Junichi Ishikawa, Michio Fujiwara, Yasuhiko Kita Department of Rheumatology, Yokohama Rosai Hospital, Kohoku-ku, Yokohama, Kanagawa, Japan Abstract: Progressive multifocal leukoencephalopathy (PML) is a central ...
Fujiwara M, Ishikawa Y, Ishikawa J, Kita Y, Kasuya T   +4 more
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Quantitative electroencephalography supports diagnosis of natalizumab-associated progressive multifocal leukoencephalopathy [PDF]

, 2019
Long-term treatment of multiple sclerosis with natalizumab (NTZ) carries the risk of a devastating complication in the form of an encephalopathy caused by a reactivation of a latent John Cunningham virus infection (progressive multifocal ...
Bernasconi, Corrado Angelo, Classen, C., Chan, Andrew, Classen, G., Gold, R., Hoepner, Robert, Brandt, C.   +6 more
core   +1 more source