Results 61 to 70 of about 711,937 (246)

JC virus-induced progressive multifocal leukoencephalopathy in a presumably healthy patient

BMC Neurology, 2022
Background JC virus (JCV) is common among healthy individuals and remains latent but may be reactivated under immunosuppressive conditions, resulting in progressive multifocal leukoencephalopathy (PML).
Xiang Wang, Jinxiu Chen, Jing Gong, Ying Wu, Xiang-hao Liu   +4 more
doaj   +1 more source

Minimal residual disease–guided ibrutinib and venetoclax in patients with chronic lymphocytic leukaemia and complex karyotype

British Journal of Haematology, EarlyView.
Minimal residual disease (MRD)–guided ibrutinib and venetoclax (IVen) achieved durable remissions and high undetectable MRD (uMRD) rates in patients with high‐risk chronic lymphocytic leukaemia (CLL). Compared with historical ibrutinib monotherapy, IVen was associated with improved progression‐free and overall survival despite presence of complex ...
Maria Kislova, Elena Dmitrieva, Elena Naumova, Margarita Pochtar, Svetlana Lugovskaya, Yury Kobzev, Alla Loban, Maria Gladysheva, Tatiana Obukhova, Bella Biderman, Andrey Sudarikov, Egor Volchkov, Maria Ivanova, Vadim Ptushkin, Andrea Visentin, Eugene Nikitin   +15 more
wiley   +1 more source

Eculizumab-related progressive multifocal leukoencephalopathy

, 2015
Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection of the CNS caused by reactivation of the polyomavirus JC (JCV). In the context of immunosuppression, JCV can reactivate and spread to brain infecting oligodendrocytes ...
Ivanovic Barbeito, Yerko, Ramos González, Ana, Gómez Cibera, Emilio, Villarejo Galende, Alberto, Hilario Barrio, Amaya, Gutiérrez Martínez, Eduardo, Abradelo De Usera, Manuel, Ruíz Morales, Juan, Morales Ruiz, Enrique   +8 more
core   +1 more source

Progressive multifocal leukoencephalopathy in an HIV patient: A case report and literature review

Clinical Case Reports, 2023
Key Clinical Message Progressive multifocal leukoencephalopathy (PML) is a rare opportunistic infection of the brain caused by reactivation of the JC virus, which can lead to a lytic infection of oligodendrocytes.
Ting Lei, Ai Deng, Lianchi Li, Ming Wang, Dongbo Wu, Taoyou Zhou   +5 more
doaj   +1 more source

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source

Brainstem progressive multifocal leukoencephalopathy

European Journal of Neurology, 2020
AbstractBackground and purposeProgressive multifocal leukoencephalopathy (PML) is a severe infection caused by the polyomavirus JC that develops in the central nervous system (CNS) of immunosuppressed patients. The infection frequently starts in the brain hemispheres and can spread into other CNS regions such as the brainstem.
Gautier Breville, Igor J. Koralnik, Patrice H. Lalive   +2 more
openaire   +4 more sources

Unmasking the Influence of Viral Micro‐RNAs on Host Immunity

Immunology &Cell Biology, EarlyView.
Viral micro‐RNAs are increasingly recognized as key modulators of host–virus interactions. They influence multiple immune functions, including antigen presentation, T‐cell activation, and cytokine signaling, while also tuning viral gene expression to promote persistence.
Riley J. K. Easton, Bernadette M. Saunders   +1 more
wiley   +1 more source

Brain Magnetic Susceptibility Changes in Patients with Natalizumab-Associated Progressive Multifocal Leukoencephalopathy

, 2015
International audienceWe investigated the brain magnetic susceptibility changes induced by natalizumab-associated progressive multifocal leukoencephalopathy.
Vermersch, Patrick, Outteryck, Olivier, Lacour, Arnaud, Deramecourt, Vincent, Pruvo, Jean-Pierre, Leclerc, Xavier, Verclytte, Sebastien, Hodel, Jerome   +7 more
core   +1 more source

Preventing infections after CD19‐directed chimeric antigen receptor T‐cell therapies for lymphoma: a consensus practice statement

Internal Medicine Journal, EarlyView.
Abstract Chimeric antigen receptor (CAR) T‐cell therapies directed against cluster of differentiation 19 (CD19) are a standard of care for relapsed or refractory B‐cell lymphomas. Infection is the leading cause of non‐relapse mortality, and this risk may persist for years after CAR T‐cell receipt.
Aine Hurley, Philip George, Gemma Reynolds, Adam Stewart, Hang Quach, Nicole O'Leary, Zoe McQuilten, Andrea S. Henden, Lynette Chee, Chan Y. Cheah, Olivia Bupha‐Intr, Emily Blyth, Ben Teh, Monica Slavin, Michael Dickinson, Robert Weinkove   +15 more
wiley   +1 more source

"barbell Sign":A diagnostic imaging finding in progressive multifocal leukoencephalopathy

, 2018
The recently proposed diagnostic algorithm for progressive multifocal leukoencephalopathy underscores the importance of imaging and emphasizes the role of the radiologist in the diagnostic workup.
Anne-Marie Du Plessis, Savvas Andronikou, Bhadelia, Rafeeque A., Rafeeque A. Bhadelia, A. Fourie Bezuidenhout, Derik Basson, Andronikou, Savvas, Basson, Derik, Christelle Ackermann, Du Plessis, Anne Marie, Ackermann, Christelle, Bezuidenhout, A. Fourie   +11 more
core   +1 more source