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[Progressive multifocal leukoencephalopathy].
Der Nervenarzt, 2016Progressive multifocal leukoencephalopathy (PML) is a disease of immunosuppressed patients caused by the JC polyomavirus (JCPyV). Due to the elevated risk in patients treated with natalizumab for multiple sclerosis (MS) and also treatment with other biologicals for different indications, the relevance of PML has increased in recent years.
Warnke C +6 more
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Progressive multifocal leukoencephalopathy in HIV
International Journal of STD and AIDS, 1997Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by infection of oligodendrocytes by JC virus. As patients with HIV survive longer with severe immunodeficiency, the incidence of PML is rising.
M, Sadler, M R, Nelson
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Revisiting JC virus and progressive multifocal leukoencephalopathy
Journal of Neurovirology, 2023Angela Rocchi +2 more
semanticscholar +1 more source
The EEG in progressive multifocal leukoencephalopathy
Electroencephalography and Clinical Neurophysiology, 1969Abstract One original case and two previously reported cases of progressive multifocal leukoencephalopathy (PML) are reviewed, with emphasis on their EEG features. In one the diagnosis could be made and confirmed by brain biopsy prior to death. The EEG findings in these three cases and those in other cases reported in the literature suggest the value
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Natalizumab-associated progressive multifocal leukoencephalopathy in Germany
Neurology, 2019Objective To evaluate characteristics relevant to diagnosis of JC polyomavirus-associated progressive multifocal leukoencephalopathy (PML), and PML risk stratification in a large national cohort of patients with multiple sclerosis during therapy with ...
Kira Blankenbach +5 more
semanticscholar +1 more source
Progressive Multifocal Leukoencephalopathy in AIDS
AIDS Patient Care, 1991CASE PRESENTATION —John Williams, MD A 42-YEAR-OLD bisexual, white man presented complaining of progressive memory loss, confusion, and difficulty speaking for 1 week. The patient had been diagnosed with acquired immunodeficiency syndrome (AIDS) a year earlier when he developed cutaneous Kaposi's sarcoma.
R E, Chaisson, D E, Griffin
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PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY
Acta Pathologica Japonica, 1981Mechanism of demyelination in progressive multifocal leukoencephalopathy (PML) was elucidated by demonstrating ultrastructurally the relationship between the affected glial cells and myelin sheaths. The myelinating cells in the central nervous system, namely ollgodendroglias, were specifically attacked by PML‐virus, with eventual primary destruction of
K, Nagashima +3 more
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Progressive Multifocal Leukoencephalopathy
Journal of Computer Assisted Tomography, 1995A case of progressive multifocal leukoencephalopathy (PML) with a classic clinical presentation but with unusual pathological and radiographic findings is reported. The pathology revealed evidence of prior hemorrhage, and imaging studies revealed focal cerebral atrophy as well as contrast enhancement on MR scans.
S, Ng +5 more
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Progressive Multifocal Leukoencephalopathy
Archives of Ophthalmology, 1977A patient had been treated for chronic lymphocytic leukemia for five years before developing visual blurring as the manifestation of occipital lobe lesions of progressive multifocal leukoencephalopathy (PML). The disease is caused by an infection of the CNS oligodendrocytes by a papovavirus, whose replication is facilitated by an impairment of the host'
R E, Appen +3 more
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Progressive Multifocal Leukoencephalopathy: A Case Study
Progress in Transplantation, 2007Progressive multifocal leukoencephalopathy is a rare, highly fatal demyelinating brain infection caused by the JC virus. This infection is associated with immunosuppressive agents and is emerging in the transplant population. There has never been a documented case of progressive multifocal leukoencephalopathy in a transplant recipient receiving ...
Vicki, McCalmont, Kristi, Bennett
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