Results 111 to 120 of about 32,319 (241)

Cocaine abuse: Longitudinal MR imaging of lasting diffused leukoencephalopathy

, 2018
Cocaine use has been known to cause a number of adverse neurological conditions, such as cerebral ischemia and posterior reversible leukoencephalopathy.
Nishant Gupta, Mark Rosovsky, Ahmed Abdelbaki, Yogesh Kumar, Anil Kumar, Kaltrina Sedaliu, Roni Manyevitch, Shuo Li   +7 more
core   +1 more source

Myelin Impairment and Regeneration in the Central Nervous System: Molecular Mechanisms, Diseases, and Prospective Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
Proper myelin formation is crucial for normal neural circuit function, while myelin deficiency can lead to neural circuit dysfunction and cognitive decline, notably in Alzheimer's disease and other central nervous system demyelinating disorders. This review summarizes central myelin's structure and function, demyelination biomarkers and pathological ...
Lihong Huang, Peng Cheng, Guangdong Liu, Yang Xiang, Zhen Hong, Weidong Le   +5 more
wiley   +1 more source

A Case of Heroin induced toxic Leukoencephalopathy [PDF]

, 2020
: Heroin-induced leukoencephalopathy comes under the category of Toxic leukoencephalopathies. We report the case of middle-aged gentleman with the history of polysubstance abuse who presented with recurrent falls, difficulty in walking and drowsiness ...
Zaidi, Saba, Sattar, Sidra
core  

Dorsolateral Cervical Cord T2 Hyperintensity in KIF1C‐Related Disease (Spastic Paraplegia 58): Two Long‐Duration Cases

Annals of Clinical and Translational Neurology
Pathogenic variants in KIF1C cause Spastic Paraplegia 58 (SPG58), typically presenting with cerebellar ataxia and spastic paraparesis. We report two unrelated patients with spastic paraparesis, cerebellar ataxia, and tremor. Whole‐exome sequence analysis
Akihiko Mitsutake, Masao Osaki, Takashi Matsukawa, Miho Osako, Chisen Takeuchi, Hiroyuki Ishiura, Jun Mitsui, Ryo Kurokawa, Harushi Mori, Yuji Takahashi, Jun Goto, Shoji Tsuji, Tatsushi Toda   +12 more
doaj   +1 more source

HIV-Associated Progressive Multifocal Leukoencephalopathy: A Case Study

Acta Medica Indonesiana, 2023
Progressive multifocal leukoencephalopathy (PML) is a rare, life-threatening, infectious, lytic, demyelinating disease that results from reactivation of the virulent JC polyomavirus (JCV) “major opportunistic infection” in immunosuppressed individuals ...
Elsayed Abed, Ahmed Farag El-adawey, Mohamed Hamed Rashad, Ahmed Essmat, Mohammed Ali, Ahmed Hassan Elsheshiny, Abdel-Ghaffar Fayed, Fathy Elbaz, Mahmoud Galal Ahmed, Zohreh Abna, Shaimaa Sayed Khater   +10 more
doaj  

Prenatal exome sequencing of fetuses with central nervous system anomalies based on prenatal ultrasound and magnetic resonance imaging diagnosis: A retrospective cohort study with a systematic review and meta‐analysis

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 10, Page 1950-1964, October 2026.
Prenatal exome sequencing significantly improves diagnostic yield over chromosomal microarray analysis for fetal CNS abnormalities, with a diagnostic yield of 16% in our cohort and 27% in the meta‐analysis. Diagnostic yields vary across different phenotypes. Abstract Introduction Fetal central nervous system (CNS) abnormalities have diverse etiologies,
Jia Yao, Yan Wang, Gang Li, Zhitao Zhang, Yuan Lv, Lizhu Chen   +5 more
wiley   +1 more source

Magnetic resonance imaging and cerebrovascular hemodynamics in (pre)-eclampsia [PDF]

, 2005
Hoge bloeddruk tijdens de zwangerschap is gevaarlijk. De mogelijke gevolgen, zoals hersenoedeem, stuipen en hersenbloedingen, eisen jaarlijks wereldwijd 50 tot 65 duizend vrouwenlevens.
Zeeman, Gerda Geertruida,, Zeeman, Gerda Geertruida   +1 more
core   +16 more sources

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

Annals of Clinical and Translational Neurology
Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection.
Jinghan Hu, Leiyun Huang, Wan Zhu, Min Peng, Qiang Gong, Jing Qian   +5 more
doaj   +1 more source

Diagnosis and Management of Infectious Encephalitis in Adults: Guidelines From the European Academy of Neurology and European Society of Clinical Microbiology and Infectious Diseases

European Journal of Neurology, Volume 33, Issue 10, October 2026.
ABSTRACT Background Encephalitis is difficult to diagnose and manage, posing a challenge to clinicians. Since the last European guidelines were published in 2010, novel causes have emerged, diagnostic processes have evolved and treatments assessed which need to be reflected in updated guidelines.
Julia Granerod, Johann Sellner, Jean‐Paul Stahl, Sylviane Defres, Alexandra Mailles, Erich Schmutzhard, Elisabeth Aurelius, Thomas Whitfield, Luca Massacesi, Maarten J. Titulaer, Pille Taba, Benedict D. Michael, Tehmina Bharucha, Lance Turtle, Brendan Sargent, Arina Tamborska, Jonathan Cattrall, Yun Huang, Eva Maria Hodel, Suzannah Lant, Glynn Webb, Rajish S. K. Shil, Shalley Dhar, Diederik van de Beek, Marie Studahl, Matthijs C. Brouwer, Uta Meyding‐Lamade, Ava Easton, Bhagteshwar Singh, Tom Solomon   +29 more
wiley   +1 more source

CSF1R ⁃ related leukoencephalopathy: from hereditary diffuse leukoencephalopathy with spheroids to primary microgliopathy

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Hereditary diffuse leukoencephalopathy with spheroids (HDLS) is a rare autosomal dominant hereditary leukoencephalopathy. Progressive neuropsychiatric symptoms and motor disorders are the main clinical manifestations, and women appear earlier than men ...
Yan⁃qiu WEI, Jun XU, Ruo⁃xi LIU, Lin LI, Zhen DONG   +4 more
doaj