Results 201 to 210 of about 32,319 (241)
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Leukoencephalopathy

Neurology, 2015
Just 11 years ago, a new genetic white matter disease, leukoencephalopathy with brainstem and spinal cord involvement and elevated lactate (LBSL), was described in 7 children and 1 teenager.1 Clinical features were dominated by progressive motor deterioration without sphincter dysfunction; half of the patients had loss of position and vibratory ...
Don, Gilden, Raphael, Schiffmann
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Concentric Lacunar Leukoencephalopathy

Archives of Neurology, 1960
The group of diseases included under the general name of "leukoencephalopathy" comprises various pathoanatomic and pathogenic conditions. Their etiology is unknown. There is no satisfactory classification, and occasionally a new, equally obscure condition is added to this heterogeneous group. The purpose of this paper is to describe an unusual and not
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Intracarotid BCNU leukoencephalopathy

Cancer, 1986
Intracarotid 1,3-bis(2-chloroethyl)-1-nitrosurea (BCNU) is now a frequently used chemotherapeutic agent for high-grade glial neoplasms. The toxicity from such therapy has not been well-documented. A 50-year-old man with a left frontoparietal grade 4 astrocytoma received three injections of intracarotid BCNU, 400 mg each, over a 2-month period.
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Progressive multifocal leukoencephalopathy

Journal of Neuroimmunology, 2011
Progressive multifocal leukoencephalopathy (PML) is a disease of the central nervous system (CNS) with destructive infection of oligodendrocytes by JC virus. PML belongs to the opportunistic infections. It is observed in patients with HIV infection, lymphoid malignancies, after organ- and stem cell transplantations and more recently in the context of ...
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Progressive Multifocal Leukoencephalopathy

Neurologic Clinics, 1984
PML is a progressive opportunistic infection of the CNS caused by a commonly occurring virus that may become manifest in the context of reduced host resistance in persons of any age. The authors review the disease and its causes, including a discussion of treatment attempts and differential diagnoses.
B R, Brooks, D L, Walker
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Progressive Multifocal Leukoencephalopathy

Archives of Internal Medicine, 1963
Progressive multifocal leukoencephalopathy (PML) is a subacute demyelinating disease apparently resulting from the selective destruction of oligodendrocytes by papovaviruses. The pathology and pathogenesis of PML are distinct from those of the other slow infections of the human nervous system.
R F, JOHNSTON   +2 more
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Reversible Leukoencephalopathy Syndrome

The American Journal of Emergency Medicine, 2010
Reversible encephalopathy syndrome is a multietiological condition, the pathophysiology of which lies in the breach of the blood-brain barrier due to increased local cerebral perfusion pressure. Patients present clinically in nonspecific ways; acute computed tomography is often unrevealing, and as such, there should be a low threshold for early ...
Kshitij, Mankad   +2 more
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Inherited Leukoencephalopathiesa

Seminars in Neurology, 2012
Abstract Leukoencephalopathies are disorders that selectively involve the white matter of the brain. Acquired causes of leukoencephalopathy include inflammatory, infectious, vascular, neoplastic, and toxic disorders. Hereditary leukoencephalopathies encompass conditions characterized by progressive destruction or loss of previously ...
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Progressive Multifocal Leukoencephalopathy

Archives of Ophthalmology, 1959
Astrom, Mancall, and Richardson1have recently directed attention to progressive multifocal leukoencephalopathy, a previously unrecognized neuropathological entity. Visual symptoms have been prominent in this disorder. As no cases have been reported in the ophthalmologic literature, the following instance of progressive multifocal leukoencephalopathy ...
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Toxic Leukoencephalopathy

New England Journal of Medicine, 2001
C M, Filley, B K, Kleinschmidt-DeMasters
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