Results 231 to 240 of about 48,917 (272)
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Peroxisomal Leukoencephalopathy
Seminars in Neurology, 2012Peroxisomal leukoencephalopathies include diseases belonging to the Zellweger spectrum and the rhizomelic chondrodysplasia punctata spectrum, as well as some single enzyme defects of peroxisomal β-oxidation. The authors present information on the clinical and diagnostic approach, and the characteristics of brain magnetic resonance imaging (MRI) in ...
Poll-The, Bwee Tien, Engelen, Marc
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Progressive Multifocal Leukoencephalopathy
CONTINUUM: Lifelong Learning in Neurology, 2008Progressive multifocal leukoencephalopathy (PML) is an opportunistic viral infection of the human CNS that has gained new importance because of AIDS and newer immunosuppressive therapies. It destroys oligodendrocytes, leading to neurologic deficits associated with demyelination.PML most commonly occurs in patients who are HIV infected, but increasing ...
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Psychiatric Clinics of North America, 2011
Leukoencephalopathy is a syndrome of neurologic deficits, including alteration of mental status, caused by pathologic changes in the cerebral white matter. The term, toxic leukoencephalopathy, encompasses a wide variety of exposures and clinical presentations.
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Leukoencephalopathy is a syndrome of neurologic deficits, including alteration of mental status, caused by pathologic changes in the cerebral white matter. The term, toxic leukoencephalopathy, encompasses a wide variety of exposures and clinical presentations.
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Neurology, 2015
Just 11 years ago, a new genetic white matter disease, leukoencephalopathy with brainstem and spinal cord involvement and elevated lactate (LBSL), was described in 7 children and 1 teenager.1 Clinical features were dominated by progressive motor deterioration without sphincter dysfunction; half of the patients had loss of position and vibratory ...
Don, Gilden, Raphael, Schiffmann
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Just 11 years ago, a new genetic white matter disease, leukoencephalopathy with brainstem and spinal cord involvement and elevated lactate (LBSL), was described in 7 children and 1 teenager.1 Clinical features were dominated by progressive motor deterioration without sphincter dysfunction; half of the patients had loss of position and vibratory ...
Don, Gilden, Raphael, Schiffmann
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Progressive Multifocal Leukoencephalopathy
Neurologic Clinics, 1984PML is a progressive opportunistic infection of the CNS caused by a commonly occurring virus that may become manifest in the context of reduced host resistance in persons of any age. The authors review the disease and its causes, including a discussion of treatment attempts and differential diagnoses.
B R, Brooks, D L, Walker
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Toxic-metabolic encephalopathies are a group of disorders in which an exogenous or endogenous substance leads to transient or permanent neuronal damage. It is an important cause of potentially reversible acute encephalopathy syndrome. The signs and symptoms of toxic encephalopathies may be relatively nonspecific, and toxicologic tests are not always ...
Gabriela Alencar, Bandeira +1 more
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Gabriela Alencar, Bandeira +1 more
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Infectious leukoencephalopathies
Leukoencephalopathy from infectious agents may have a rapid course, such as human simplex virus encephalitis; however, in many diseases, it may take months or years before diagnosis, such as in subacute sclerosing panencephalitis or Whipple disease. There are wide geographic distributions and susceptible populations, including both immunocompetent and ...David, Jakabek +2 more
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Concentric Lacunar Leukoencephalopathy
Archives of Neurology, 1960The group of diseases included under the general name of "leukoencephalopathy" comprises various pathoanatomic and pathogenic conditions. Their etiology is unknown. There is no satisfactory classification, and occasionally a new, equally obscure condition is added to this heterogeneous group. The purpose of this paper is to describe an unusual and not
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