Results 241 to 250 of about 48,917 (272)

Reversible Leukoencephalopathy Syndrome

The American Journal of Emergency Medicine, 2010
Reversible encephalopathy syndrome is a multietiological condition, the pathophysiology of which lies in the breach of the blood-brain barrier due to increased local cerebral perfusion pressure. Patients present clinically in nonspecific ways; acute computed tomography is often unrevealing, and as such, there should be a low threshold for early ...
Kshitij, Mankad, Edward, Hoey, Ki Sing, Yap   +2 more
openaire   +2 more sources

Progressive Multifocal Leukoencephalopathy

Seminars in Neurology, 1999
Before the AIDS epidemic, progressive multifocal leukoencephalopathy (PML) was a rare disorder occurring most often in association with leukemia and lymphoma. Current estimates indicate that PML ultimately develops in up to 5% of all patients with AIDS.
J R, Berger, E O, Major
openaire   +2 more sources

Toxic Leukoencephalopathy

2012
The white matter of the brain is vulnerable to a wide variety of toxins. Leukoencephalopathy is being increasingly recognized in a number of different patient populations. The detection of early and subtle toxin effects has been facilitated by the advent of magnetic resonance imaging, which offers better resolution of white matter than other ...
openaire   +2 more sources

MRI in methotrexate-related leukoencephalopathy: Disseminated necrotising leukoencephalopathy in comparison with mild leukoencephalopathy

Neuroradiology, 2003
We report two fatal cases of methotrexate (MTX)-induced disseminated necrotising leukoencephalopathy (DNL) in which MRI was repeated from the onset. Initial T2-weighted images showed multiple areas of high signal, mainly in deep cerebral white matter, which on follow-up, spread and coalesced to involve the entire white matter.
M, Oka, S, Terae, R, Kobayashi, Y, Sawamura, K, Kudoh, K K, Tha, M, Yoshida, M, Kaneda, Y, Suzuki, K, Miyasaka   +9 more
openaire   +2 more sources

Cree Leukoencephalopathy and Other Leukoencephalopathies Involving Arcuate Fibers

Radiology, 2001
Editor: We read with great interest the article by Dr Alorainy and colleagues in the November 1999 issue of Radiology (1). The authors nicely presented computed tomographic and magnetic resonance (MR) imaging findings of a rare and lethal disorder, Cree leukoencephalopathy, in 12 patients whose diagnoses were made clinically or at autopsy.
U, Senol, K, Karaali
openaire   +2 more sources

Progressive Multifocal Leukoencephalopathy

Archives of Internal Medicine, 1963
Progressive multifocal leukoencephalopathy (PML) is a subacute demyelinating disease apparently resulting from the selective destruction of oligodendrocytes by papovaviruses. The pathology and pathogenesis of PML are distinct from those of the other slow infections of the human nervous system.
R F, JOHNSTON, R A, GREEN, J T, HEADINGTON   +2 more
openaire   +2 more sources

LEUKOENCEPHALOPATHIES AND LEUKODYSTROPHIES

Continuum, 2010
The leukoencephalopathies encompass a heterogeneous group of disorders that involve the brain white matter. The cause may be acquired or inherited; in the latter case, mutations have been found in genes that encode protein components of the myelin membrane or enzymes implicated in the turnover of myelin. In patients with cognitive dysfunction and white
openaire   +2 more sources

Progressive Multifocal Leukoencephalopathy

Archives of Ophthalmology, 1959
Astrom, Mancall, and Richardson1have recently directed attention to progressive multifocal leukoencephalopathy, a previously unrecognized neuropathological entity. Visual symptoms have been prominent in this disorder. As no cases have been reported in the ophthalmologic literature, the following instance of progressive multifocal leukoencephalopathy ...
openaire   +2 more sources

Progressive Multifocal Leukoencephalopathy

Radiology, 1976
The radionuclide, radiographic and pathologic findings in a patient with progressive multifocal leukoencephalopathy were correlated. Radionuclide imaging demonstrated the largest two of the many lesions observed at pathology. On repeated studies, one of the lesions developed a "doughnut" sign due to central necrosis. Cerebral angiography disclosed only
J, Kirsh, L, Rosenthall, M H, Finlayson, R, Wee   +3 more
openaire   +2 more sources

Progressive multifocal leukoencephalopathy

Current Infectious Disease Reports, 2001
Progressive multifocal leukoencephalopathy is a subacute demyelinating disease that occurs in patients with defects in cell-mediated immunity, including those with AIDS and lymphoproliferative disorders. It is caused by reactivation of JC virus (JCV), which infects 70% to 90% of the population by adulthood, but remains latent in normal hosts.
Anna R., Thorner, Joel T., Katz
openaire   +2 more sources