Results 131 to 140 of about 66,344 (289)
The Saudi Journal of GastroenterologyBackground: Azathioprine, a common inflammatory bowel disease (IBD) treatment, carries a myelosuppression risk, particularly leukopenia. Thiopurine methyltransferase (TPMT) genotyping can predict azathioprine-induced leukopenia (AIL), but data on TPMT ...
Yaser K. Meeralam +7 more
doaj +1 more source
Viruses, Periodontitis, and Systemic Diseases
Journal of Periodontal Research, EarlyView.This narrative review aimed to summarize current evidence on the viral involvement in periodontitis and its relevance for systemic diseases. The oral cavity acts as an active viral reservoir and dissemination platform, where virus–microbiome interactions may promote dysbiosis, periodontitis progression, and systemic inflammatory effects, while the ...
Kim Natalie Solte +2 more
wiley +1 more source
Cytopenias in Compensated Versus Decompensated Liver Function: Is There a Difference?
Gastroenterology InsightsBackground/Objectives: Patients with liver cirrhosis (LC) present hematological abnormalities with multiple etiologies. As liver function deteriorates, these abnormalities become more evident, conferring a higher risk of morbidity and mortality.
Elda Victoria Rodríguez-Negrete +7 more
doaj +1 more source
Journal of Veterinary Pharmacology and Therapeutics, EarlyView.ABSTRACT The misuse and abuse of veterinary anesthetic and analgesic agents pose significant public health risks, particularly with the growing presence of ultrapotent opioids and other anesthetics in the illicit drug trade. In response, there is increasing emphasis on incorporating medication safety training into veterinary curricula.
Margene Anderson +2 more
wiley +1 more source
A Population Pharmacokinetic Model of Gentamicin in Hospitalized Neonatal Foals
Journal of Veterinary Pharmacology and Therapeutics, EarlyView.ABSTRACT Information on safe and effective gentamicin dosing in foals is limited. This study aimed to provide guidance regarding optimal dosing regimens by means of a population pharmacokinetic (popPK) model. Gentamicin plasma concentration of 290 samples from 72 hospitalized foals (≤ 14 days old), treated with intravenous (IV) gentamicin, was measured
Astrid J. van den Brom‐Spierenburg +12 more
wiley +1 more source
Oral Diseases, EarlyView.ABSTRACT Objective Oral cavity squamous cell carcinoma (OCSCC) is the predominant subtype of head and neck squamous cell carcinoma in Taiwan. Despite the guideline‐recommended adjuvant chemoradiotherapy (CRT) for advanced pathological risk factors, long‐term survival remains suboptimal.
Hsueh‐Ju Lu +7 more
wiley +1 more source
Transplant Infectious Disease, EarlyView.During the 2023–2024 Argentine dengue outbreak, 33 patients with hematological disease showed high complication rates, frequent hospitalization (64%), severe thrombocytopenia (90%), and 6% dengue‐attributable mortality. Transfusion‐associated cases were documented.
Gustavo Adolfo Méndez +16 more
wiley +1 more source
Impact of Letermovir on Voriconazole Concentrations in Lung Transplant Patients
Transplant Infectious Disease, EarlyView.Concomitant letermovir was associated with lower voriconazole exposure and reduced attainment of commonly used efficacy thresholds in lung transplant recipients. Routine therapeutic drug monitoring after letermovir initiation is recommended, and empiric voriconazole dose escalation may be needed to avoid subtherapeutic exposure. ABSTRACT Background The
Leah Georgiades +6 more
wiley +1 more source