Results 141 to 150 of about 66,344 (289)

Reactogenicity and Immunogenicity of RSV Vaccines in Immunocompromised Individuals With Hematological Malignancies

open access: yesTransplant Infectious Disease, EarlyView.
In adults with hematologic malignancies, RSV vaccination was safe and induced antibody and T‐cell responses. However, antibody levels were lower and declined more rapidly than in healthy controls. While early immune responses were evident, reduced magnitude and durability of protection suggest the need for optimized vaccination strategies in this high ...
Alisse Hannaford   +32 more
wiley   +1 more source

Serial Blood Microbiome Profiles in Kidney Transplant Recipients Reveal Evidence of Circulating Gut and Non‐Gut Derived Microbial DNA

open access: yesTransplant Infectious Disease, EarlyView.
In this prospective cohort study, we profiled the blood microbiome in kidney transplant recipients over time. We detected a low abundance of microbial DNA in half of the blood specimens. In a small subset, we also detected gut bacterial taxa in the blood of kidney transplant recipients.
Alex DeVito   +10 more
wiley   +1 more source

Haematological Manifestations in Children with Extended Drug-Resistant Salmonella Typhi Infections in a Tertiary Care Hospital

open access: yesJLUMHS
OBJECTIVE: To analyze the haematological parameters in children affected by extended drug-resistant salmonella typhi (XDR S. typhi) infections in a Tertiary care hospital.
Nazish Tahir   +5 more
doaj   +1 more source

Retrospective Application of the Current International Myeloma Working Group Disease Definitions in 20 Cats With Immunoglobulin Secreting Neoplasms

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT Studies describing feline myeloma related diseases (MRD) are limited and reported prognostic indicators are inconsistent. Cats more commonly exhibit visceral plasma cell tumours (PCTs) than marrow‐predominant disease, suggesting that diagnostic approaches adapted from the International Myeloma Working Group (IMWG) criteria, incorporating ...
Christina M. Jeffries   +5 more
wiley   +1 more source

Transient Atrioventricular Block Secondary to Coronary Artery Embolism From Infective Endocarditis Following CAR T‐Cell Therapy

open access: yesJournal of Arrhythmia, Volume 42, Issue 6, December 2026.
Silent infective endocarditis after CAR‐T therapy caused septic embolic occlusion of a septal coronary branch, producing localized myocardial infarction involving the His bundle region and transient complete atrioventricular block. This case highlights a rare, pathologically confirmed mechanism of conduction disturbance.
Kento Kito   +8 more
wiley   +1 more source

Association Between BMI and the Efficacy and Safety of CDK4/6 Inhibitors in HR+/HER2− Advanced Breast Cancer: A Multicenter Retrospective Propensity Score Matched Cohort Study (CAMELIA)

open access: yesMedComm – Oncology, Volume 5, Issue 4, December 2026.
This multicenter real‐world study showed that higher BMI (≥ 25 kg/m2) was independently associated with improved PFS in patients with HR+/HER2− advanced breast cancer receiving CDK4/6 inhibitors. Safety outcomes were comparable between BMI groups, and the findings were consistent across alternative BMI thresholds, suggesting the potential prognostic ...
Min Tian   +12 more
wiley   +1 more source

Endotoxins and Biological Implications—Review

open access: yesPublic Health Challenges, Volume 5, Issue 4, December 2026.
Graphical overview of endotoxin sources, exposure routes, biological effects, detection methods, and routes of elimination. ABSTRACT Endotoxins, also known as lipopolysaccharides (LPSs), are structural components of the outer membrane of Gram‐negative bacteria and some cyanobacteria.
Uzair Ishtiaq   +5 more
wiley   +1 more source

Prognostic significance of leukopenia during the induction phase in adult B cell acute lymphoblastic leukemia

open access: yes, 2018
Chongyun Xing,1,* Bin Liang,1,* Junqing Wu,1 Qianqian Yang,1 Gang Hu,1 Ye Yan,1 Yu Zhang,1 Songfu Jiang,1 Kang Yu,1 Jianhua Feng1,2 1Division of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, PR China; 2Division of ...
Wu J   +9 more
core  

Renal Function–Guided Valganciclovir Dosing and Ganciclovir Exposure Variability: A Population Pharmacokinetic Simulation Study

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 6, December 2026.
ABSTRACT Background Ganciclovir (GCV) exposure after standard valganciclovir (VGCV) prophylaxis is highly variable. Guidelines recommend Cockcroft–Gault for renal dose adjustment. We evaluated whether Cockcroft–Gault‐based dosing achieves the target prophylactic exposure (AUC0‐24h: 40–60 mg.h/L) and whether MDRD or CKD‐EPI alters exposure.
Franck Maizaud   +6 more
wiley   +1 more source

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