Results 151 to 160 of about 66,344 (289)

Unsupervised Global CBC/RUO/CPD Phenotyping Identifies Haematological Clusters Enriched for Thrombocytopenia Severity and Mechanisms

International Journal of Laboratory Hematology, Volume 48, Issue 6, Page 1385-1395, December 2026.
ABSTRACT Introduction Thrombocytopenia has heterogeneous mechanisms, including peripheral destruction, consumption, and reduced marrow production. This study developed an unsupervised global complete blood count/research‐use‐only/cell population data (CBC/RUO/CPD) phenotyping model and evaluated post hoc whether thrombocytopenia severity and clinically
Mohammad A. Altememi, Emmanuel J. Favaloro, Md Zahidul Islam, Sara Ng, Danny Hsu, Abishek B. Santhakumar   +5 more
wiley   +1 more source

Prevalence and impact of Thiopurine S-methyltransferase (TPMT) and Nudix hydrolase 15 (NUDT15) polymorphisms on the occurrence of myelosuppression in Thai patients with inflammatory bowel disease receiving thiopurine therapy. [PDF]

Crohns Colitis 360
Phoojaroenchanachai R, Chaemsupaphan T, Sattayalertyanyong O, Subdee N, Phaophu P, Salaemae M, Limsrivilai J.   +6 more
europepmc   +1 more source

Bispecific antibodies targeting B‐cell maturation antigen in multiple myeloma: Current clinical applications, challenges and future directions

Cancer, Volume 132, Issue 22, 15 November 2026.
Abstract Anti‐B cell maturation antigen (BCMA) therapies, including antibody‐drug conjugates, chimeric antigen receptor T cells, and bispecific antibodies (bsAbs), have recently revolutionized the treatment landscape of multiple myeloma. This review outlines the biologic rationale for targeting BCMA and sheds light on the mechanism of action of bsAbs ...
Enrica Manzato, Gloria Cocchetto, Simona Barbato, Michele Puppi, Simone Masci, Elena Zamagni   +5 more
wiley   +1 more source

[Clinical characteristics of primary Sjögren syndrome with leukopenia]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Zhu Z, Cheng F, Wang Y, Liu Y, Ai X, Zhang K, Zhao F.   +6 more
europepmc   +1 more source

DPYD and UGT1A1 Genotype‐Based Dosing for Fluoropyrimidines and Irinotecan Chemotherapy: Variant‐Specific Impact on Treatment Intensity and Toxicity

International Journal of Cancer, Volume 159, Issue 10, Page 2512-2524, 15 November 2026.
Pre‐treatment DPYD and UGT1A1 genotyping is increasingly used to prevent fluoropyrimidine‐ and irinotecan‐related toxicity, but variant‐specific real‐world effects remain unclear. In an unselected cohort of cancer patients with actionable genotypes, genotype‐driven dosing improved safety while preserving treatment exposure in high‐risk DPYD c.1905+1G>A
Martina Gambron, Elena Peruzzi, Samantha Perfler, Marcella Montico, Riccardo Cecchin, Elena De Mattia, Michele Spina, Camilla Lisanti, Serena Corsetti, Luisa Foltran, Fabio Puglisi, Rossana Roncato, Erika Cecchin   +12 more
wiley   +1 more source

Inclusion Complexations of Levamisole and Cocaine With Molecular Baskets. Fluorescence Displacement Assay for Detection of Cocaine and Its Adulterant Levamisole in Aqueous Media

Chemistry – A European Journal, Volume 32, Issue 41, 3 November 2026.
Levamisole is a common adulterant found in street‐distributed cocaine. Molecular baskets have been shown to form stable inclusion complexes with both substances. While levamisole inserts its benzene into the basket's cavity, cocaine utilizes its bicyclic ring for encapsulation.
Christopher T. Mortensen, Carson E. Ward, Nitesh Kumar, Logan Willemann, Ryan Lutz, Kailey Hughes, Zheng Zheng, Jovica D. Badjić   +7 more
wiley   +1 more source

Alemtuzumab Induction via Intravenous vs. Subcutaneous Administration in Pediatric Kidney Transplantation. [PDF]

Pediatr Transplant
Pizzo H, Barbera A, Westreich K, Seifert ME, Mirocha J, Kirshner K, Puliyanda D.   +6 more
europepmc   +1 more source

What Is Your Diagnosis? Blood Smear From a Mixed‐Breed Dog

Veterinary Clinical Pathology, EarlyView.
Laura S. Peres, Lina C. Bilhalva, Camila B. E. Mello, Abílio G. Silva, Andrea P. Santos, Stella F. Valle   +5 more
wiley   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, Volume 78, Issue 11, Page 1593-1601, November 2026.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

Clinico-Hematological Evaluation of Bicytopenia in Adults: A Hospital-based Observational Study. [PDF]

Ann Afr Med
Kuchanur V, Patil A, Rao SS.
europepmc   +1 more source