Phase I study of everolimus and mitomycin C for patients with metastatic esophagogastric adenocarcinoma [PDF]
, 2013 This study aimed at determining the recommended dose of the mammalian target of rapamycin inhibitor everolimus in combination with mitomycin C (MMC) in patients with previously treated metastatic esophagogastric cancer.
Atmaca, Akin +5 more
core +1 more source
Frontiers in Pharmacology, 2023 Leukopenia caused by radiation hinders the continuous treatment of cancers. Danggui Buxue Decoction (DBD) has been widely used in clinical owing to low toxicity and definite therapeutic effects to increase leukocytes.
Wei Chen +13 more
doaj +1 more source
The mouse and ferret models for studying the novel avian-origin human influenza A (H7N9) virus. [PDF]
, 2013 BackgroundThe current study was conducted to establish animal models (including mouse and ferret) for the novel avian-origin H7N9 influenza virus.FindingsA/Anhui/1/2013 (H7N9) virus was administered by intranasal instillation to groups of mice and ...
Bao, Linlin +19 more
core +3 more sources
Murine cytomegalovirus genomic material in marrow cells; relation to altered leukocyte counts during sublethal infection of mice [PDF]
, 1987 To investigate infection of hematopoietic cells by murine cytomegalovirus (MCMV), we used in situ hybridization to detect MCMV genomic material in marrow cells during sublethal infection of three-week-old mice.
Bale, J. F. +4 more
core +1 more source
Transient Neutropenia in Immunocompetent Infants with Respiratory Syncytial Virus Infection
Viruses, 2021 The incidence of neutropenia and the association between neutropenia and severity of respiratory symptoms among infants with respiratory syncytial virus (RSV) infections remain to be elucidated.
Tatsuya Korematsu, Hiroshi Koga
doaj +1 more source
Hemodialysis membrane-related neutrophil dysfunctions and pentoxifylline - a pilot study [PDF]
, 1990 Hemodialysis treatment is associated with activation of neutrophil granulocytes. Pentoxifylline has been shown to inhibit neutrophil activation in vitro and in vivo.
Hoffmann, H. +3 more
core +1 more source
A retrospective study of 134 patients with cervical region Kikuchi–Fujimoto disease
Laryngoscope Investigative Otolaryngology, 2023 Background To explore the clinical and laboratory features, therapy and prognosis of Kikuchi–Fujimoto disease (KFD) in the cervical region. Methods We retrospectively reviewed the medical records of 134 patients who were diagnosed and treated with KFD ...
Jianzhi Liu +6 more
doaj +1 more source
Prognostic value of chemotherapy-induced leukopenia in small-cell lung cancer
Cancer Biology & Medicine, 2013 Objective:Chemotherapy is the standard treatment for small-cell lung cancer (SCLC), and leukopenia is a common side effect. This study assesses whether chemotherapy-induced leukopenia is a predictor of efficacy and whether it is associated with the ...
Wei Liu, Cui-Cui Zhang, Kai Li
doaj +1 more source
Effect of mycophenolate mofetil on the white blood cell count and the frequency of infection in systemic lupus erythematosus. [PDF]
, 2015 Leukopenia is a common manifestation of SLE. Addition of immunosuppressive therapy in a SLE patient who is already leukopenic is a clinical concern. It could worsen leukopenia, increase the risk of infection, or both. The aim of this study was to analyze
Magder, Laurence S. +2 more
core +2 more sources
Arthritis Care &Research, EarlyView.Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner +14 more
wiley +1 more source