Results 41 to 50 of about 66,344 (289)

Leukopenia and leukocytosis as strong predictors of COVID‐19 severity: A cross‐sectional study of the hematologic abnormalities and COVID‐19 severity in hospitalized patients

Health Science Reports, 2023
Background and Aims Predicting severe disease is important in provocative decision‐making for the management of patients with the coronavirus disease 2019 (COVID‐19); However, there are still some controversies about the COVID‐19's severity predicting ...
Fateme Sharafi, Reza Jafarzadeh Esfehani, AmirAli Moodi Ghalibaf, Lida Jarahi, Ali Shamshirian, Mahnaz Mozdourian   +5 more
doaj   +1 more source

Radiation-free or Chemo-free: Rethinking the Best Strategy for PD-L1-High, Unresectable Stage III NSCLC. [PDF]

Precis Radiat Oncol
This article discusses the emerging radiotherapy‐free and chemo‐free strategies in PD‐L1–high, unresectable stage III NSCLC, reviewing the Evolution trial and comparing it with existing treatments. We highlight the need for further research to validate these approaches and ensure safe de‐escalation without compromising ...
Xiang Y, Bi N.
europepmc   +2 more sources

Peripheral Blood DNA Methylation Changes Precede Lymphoma Diagnosis in Primary Sjögren's Disease

Arthritis &Rheumatology, EarlyView.
Objective Primary Sjögren's disease (SjD) is a systemic autoimmune disease associated with an increased risk of lymphoma. The molecular mechanisms underlying lymphomagenesis remain poorly understood, and sensitive biomarkers for early identification of patients at high risk of developing lymphoma are lacking.
Hanna Lidberg, Cecilia Fugmann, Juliana Imgenberg‐Kreuz   +2 more
wiley   +1 more source

Prognostic value of chemotherapy-induced leukopenia in small-cell lung cancer

Cancer Biology & Medicine, 2013
Objective:Chemotherapy is the standard treatment for small-cell lung cancer (SCLC), and leukopenia is a common side effect. This study assesses whether chemotherapy-induced leukopenia is a predictor of efficacy and whether it is associated with the ...
Wei Liu, Cui-Cui Zhang, Kai Li
doaj   +1 more source

Facing dengue fever - our first experience [PDF]

Vojnosanitetski Pregled, 2017
Introduction. Dengue fever is a mosquito-borne disease caused by dengue virus, endemic in tropical and subtropical regions, where it is mostly imported from. The most common clinical form is classic dengue fever.
Cvjetković Dejan, Mikić Sandra, Hrnjaković-Cvjetković Ivana   +2 more
doaj   +1 more source

Development and Validation of a Novel UHPLC-MS/MS Method for the Quantification of Plinabulin in Plasma and Its Application in a Pharmacokinetic Study with Leukopenic Rats

Pharmaceuticals, 2023
Plinabulin, a new antitumor drug developed from marine natural products that targets microtubules in cancer cells, is currently being tested in a phase III clinical study. Plinabulin has been clinically proven to be effective on leukopenia.
Xiaochen Niu, Dan Chen, Wei He, Yu Tang, Jianchun Zhao   +4 more
doaj   +1 more source

Leukopenia in the critically ill patient

, 2014
The diagnosis of leukopenia can be particularly challenging in the critically ill patient, since a reduced number of white blood cells can be associated with many different systemic or hematological disorders.
AGBEDJRO, ANTOINETTE, Giorgio Berlot, PRESELLO, BARBARA, Antoinette Agbedyro, BERLOT, GIORGIO, Barbara Presello   +5 more
core   +1 more source

Pharmacokinetics, Effectiveness and Safety of Certolizumab Pegol in Children and Adolescents With Active Juvenile Idiopathic Arthritis: 9+‐Year Results From a Multicenter, Open‐Label Study

Arthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to assess the pharmacokinetics, effectiveness, safety, and immunogenicity of certolizumab pegol (CZP) in polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods Pediatric Arthritis Study of Certolizumab Pegol (NCT01550003), a multicenter, open‐label study, enrolled patients aged 2 to 17 years with ...
Hermine I. Brunner, Lyudmila Grebenkina, Irina Nikishina, Ekaterina Alexeeva, Vyacheslav Chasnyk, Carlos Abud‐Mendoza, Nadina Rubio‐Pérez, Heinrike Schmeling, María del Rocio Maldonado‐Velázquez, Diane Brown, Andrew Zeft, Esi Morgan, C. Egla Rabinovich, Daniel Kingsbury, Hulya Bukulmez, Beth Gottlieb, Thomas Griffin, Lisa Imundo, Stacey Tarvin, Earl Silverman, Laura Shaughnessy, Saori Shimizu, Paulette Williams, Rocío Lledó‐García, Gauri Utturkar, Baran Ufuktepe, Alberto Martini, Daniel J. Lovell, Nicolino Ruperto, the Paediatric Rheumatology International Trials Organisation (PRINTO); the Pediatric Rheumatology Collaborative Study Group (PRCSG), Hermine I. Brunner, Lyudmila Grebenkina, Irina Nikishina, Ekaterina Alexeeva, Vyacheslav Chasnyk, Carlos Abud‐Mendoza, Nadina Rubio‐Pérez, Heinrike Schmeling, María del Rocio Maldonado‐Velázquez, Diane Brown, Andrew Zeft, Esi Morgan, C. Egla Rabinovich, Daniel Kingsbury, Hulya Bukulmez, Beth Gottlieb, Thomas Griffin, Lisa Imundo, Stacey Tarvin, Earl Silverman, Alberto Martini, Daniel L. Lovell, Nicolino Ruperto   +52 more
wiley   +1 more source

Supplementary Figure from Identification of Two Genetic Loci Associated with Leukopenia after Chemotherapy in Patients with Breast Cancer

, 2022
Supplementary Figure from Identification of Two Genetic Loci Associated with Leukopenia after Chemotherapy in Patients with Breast ...
Georg Heinrich (15039287), Brigitte Rack (61954), Jane Romm (14969476), Matthias Ruebner (282231), Ebony Madden (15039290), Liewei Wang (142596), Julie M. Cunningham (15038880), Wolfgang Janni (15039299), Andreas Schneeweiss (14945304), Richard M. Weinshilboum (7375184), Alvaro N.A. Monteiro (15039302), Hanna Huebner (582176), Kim Doheny (13434551), Tanja N. Fehm (8670363), Duan Liu (15038871), Gregory D. Jenkins (14897834), Paulo C. Lyra (15039275), Hans Tesch (6867971), Alexander Hein (15039278), Matthias W. Beckmann (8115809), Liang Li (15039293), Erin E. Carlson (1371462), Lothar Häberle (395470), Diether Lambrechts (15023694), Brooke L. Fridley (15039296), James N. Ingle (14962461), Steve Scully (202724), Peter A. Fasching (9630950), Daniel J. Schaid (3716326), Arif B. Ekici (15039281), Jess Shen (5920934), Andre Reis (15039284)   +31 more
core   +3 more sources

Forest plot of meta-analysis for leukopenia (grade 3/4).

, 2018
Forest plot of meta-analysis for leukopenia (grade 3/4).
Zhao Dehua (4989911), Chu Mingming (4989914), Wang Jisheng (4989917)   +2 more
core   +1 more source