Results 61 to 70 of about 60,964 (206)

Interleukin-2 is associated with cytopenias in systemic lupus erythematosus

Autoimmunity
Interleukin 2 (IL-2) is a cytokine essential for the development and function of regulatory T cells, which are key players in maintaining immune tolerance by suppressing autoreactive lymphocytes.
Miguel Á. González-Gay, Fuensanta Gómez-Bernal, Juan C. Quevedo-Abeledo, Beatriz Tejera-Segura, Cristina Gómez-Moreno, Enrique García-Barrera, Luisa M. Villar, J. Gonzalo Ocejo-Vinyals, Raquel Largo, Iván Ferraz-Amaro   +9 more
doaj   +1 more source

Cytopenia occurrence in kidney transplant recipients within early post-transplant period

Journal of Research in Pharmacy Practice, 2017
Objective: This study assessed incidence, severity, and time to occurrence of drug-induced leukopenia/thrombocytopenia within 1st month after kidney transplantation.
Atefeh Jafari, Parisa Najivash, Mohammad-Reza Khatami, Simin Dashti-Khavidaki   +3 more
doaj   +1 more source

173. Does the correlation between chemotherapy-induced leukopenia with response in locally advanced breast cancer exist? [PDF]

, 2003
PurposeThe correlation between chemotherapy-induced toxicity and treatment outcome in cancer patients has not been thoroughly studied. Our aim was to evaluate whether leukopenia following primary chemotherapy may be predictive for response in patients ...
J. Jassem, Badzio, A., M. Wełnicka-Jaśkiewicz, Tomczak-Hałaburda, J., J. Tomczak-Hałaburda, Jereczek-Fossa, B., B. Jereczek-Fossa, Wełnicka-Jaśkiewicz, M., W. Rogowski, Jassem, J., A. Badzio, Rogowski, W.   +11 more
core   +1 more source

Immuno-Haematological Abnormalities of HIV-Infected Patients Before and After Initiation of Highly Active Antiretroviral Therapy in the Antiretroviral Therapy Clinics of Six Health Facilities at Dessie Town, Northeast Ethiopia

Journal of Blood Medicine, 2022
Mihret Tilahun,1 Alemu Gedefie,1 Endris Ebrahim,1 Abdurahaman Seid,1 Abdurrahman Ali,1 Agumas Shibabaw,1 Melaku Ashagrie Belete,1 Mesfin Fiseha,1 Melkam Tesfaye,1 Hussen Ebrahim,1 Admasu Abera2 1Department of Medical Laboratory Sciences, College of ...
Tilahun M, Gedefie A, Ebrahim E, Seid A, Ali A, Shibabaw A, Belete MA, Fiseha M, Tesfaye M, Ebrahim H, Abera A   +10 more
doaj  

Leukopenia in Familial Mediterranean Fever: Case Series and Literature Review with Special Emphasis on Pathogenesis [PDF]

, 2014
Leukopenia is a blood disease in which the number of circulating white blood cells diminishes. All underlying causes of leukopenia are not yet known. The subjects of this study are 15 leukopenic patients who were assessed by a systemic workup, including ...
Aslan, DENİZ
core   +1 more source

Diagnostic accuracy of NUDT15 gene variants for thiopurine-induced leukopenia: a systematic review and meta-analysis [PDF]

, 2018
We herein conducted a systematic review and meta-analysis of published studies to estimate diagnostic accuracy of NUDT15 gene polymorphisms for detection of thiopurine-induced leukopenia. Eligible studies were identified through a comprehensive search on
Genazzani, Armando, Canonico, Pier Luigi, Cargnin, Sarah, Terrazzino, Salvatore   +3 more
core   +1 more source

Severe leukopenia in Staphylococcus aureus-necrotizing, community-acquired pneumonia: risk factors and impact on survival. [PDF]

, 2013
International audienceBACKGROUND: Necrotizing pneumonia attributed to Panton-Valentine leukocidin-positive Staphylococcus aureus has mainly been reported in otherwise healthy children and young adults, with a high mortality rate.
Khanafer, Nagham, Nicolas Sicot, Jérôme Etienne, Michèle Bès, Dumitrescu, Oana, Gillet, Yves, Yves Gillet, Gérard Lina, Tristan, Anne, François Vandenesch, Etienne, Jérôme, Vandenesch, François, Lina, Gérard, Meyssonier, Vanina, Oana Dumitrescu, Bès, Michèle, Philippe Vanhems, Anne Tristan, Vanina Meyssonier, Sicot, Nicolas, Vanhems, Philippe, Nagham Khanafer   +21 more
core   +1 more source

Two cases of acute leukopenia induced by colchicine with concurrent immunosuppressants use in Behçet's disease. [PDF]

, 2008
Colchicine-induced leukopenia usually occurrs in intentional or accidental overdoses or inappropriate use in combination with intravenous and oral colchine; however, there have been several reports of hematologic toxicity in short-term and small-dose ...
Kyu-Yeop Lee, 장재용, 방동식, Jae Yong Chang, Dongsik Bang, Do Young Kim   +5 more
core   +1 more source

Early Assessment of Thiopurine Metabolites Identifies Patients at Risk of Thiopurine-Induced Leukopenia in Inflammatory Bowel Disease [PDF]

, 2017
BACKGROUND AND AIMS: Only a quarter of thiopurine-induced myelotoxicity in IBD patients is related to TPMT deficiency. We determined the predictive value of 6-thioguanine nucleotide (6TGN) and 6-methylmercaptopurine ribonucleotide (6MMPR) concentrations ...
Derijks, Luc J J, Vermeulen, Sita H, Verbeek, André L M, van Marrewijk, Corine J, Klungel, Olaf H, Guchelaar, Henk-Jan, de Jong, Dirk J, Engels, Leopold G J B, Coenen, Marieke J H, Wong, Dennis R, Scheffer, Hans, Franke, Barbara, Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Hooymans, Piet M   +14 more
core   +3 more sources

Leukocyte Count in Solid Organ Transplant Recipients After SARS-CoV-2 mRNA Vaccination and Infection

Vaccines
Background: Solid organ transplant (SOT) recipients are at risk of severe COVID-19. Vaccination is an important preventive measure but may have side effects, including decreased leukocyte counts. We aimed to describe the prevalence and relative incidence
Marita Kern, Sebastian Rask Hamm, Christian Ross Pedersen, Dina Leth Møller, Josefine Amalie Loft, Rasmus Bo Hasselbalch, Line Dam Heftdal, Mia Marie Pries-Heje, Michael Perch, Søren Schwartz Sørensen, Allan Rasmussen, Peter Garred, Kasper Karmark Iversen, Henning Bundgaard, Caroline A. Sabin, Susanne Dam Nielsen   +15 more
doaj   +1 more source