Results 81 to 90 of about 66,344 (289)

Nudix hydrolase 15 deficiency and azathioprine toxicity in a liver transplant recipient: A case report

open access: yesJPGN Reports, EarlyView.
Abstract Thiopurines, such as azathioprine (AZA), are among the immunosuppressants used to prevent allograft rejection. Thiopurines are metabolized by thiopurine S‐methyltransferase (TPMT) and nudix hydrolase 15 (NUDT15) enzymes, and their functions are highly influenced by genetic variation. We present a 6‐year‐old female with recurrent acute cellular
Jenny Q. Nguyen   +4 more
wiley   +1 more source

Early Leukocyte Profiles in Preterm Infants Born to Mothers with Systemic Lupus Erythematosus: An Exploratory Matched Cohort Study

open access: yesChildren
Background/Objectives: Maternal systemic lupus erythematosus (SLE) is associated with preterm birth, but whether maternal disease activity influences early neonatal hematologic profiles beyond developmental immaturity remains unclear.
Hikaru Takahashi   +4 more
doaj   +1 more source

Leukopenia and neutropenia in chronic hepatitis C patients with various underlying combination antiviral therapy

open access: yesЖурнал инфектологии, 2014
The aim of this research is the study of the dynamics of the content of leukocytes and neutrophils in the blood of patients with chronic hepatitis C combination therapy against standard or pegylated interferon combined with ribavirin.
K. V. Zhdanov   +3 more
doaj   +1 more source

Human immunodeficiency virus infection mimicking very early onset inflammatory bowel disease

open access: yesJPGN Reports, EarlyView.
Abstract Very early onset inflammatory bowel disease (VEO‐IBD), defined as diagnosis before 6 years of age, is often associated with immune dysregulation and monogenic etiologies; however, infectious mimics may be overlooked in low‐prevalence regions. We report a 4‐year‐old male with poor weight gain, intermittent diarrhea, elevated fecal calprotectin,
Rasha Abi Radi Abou Jaoudeh   +2 more
wiley   +1 more source

Retrospective analysis of leukopenia in apheresis platelet donors

open access: yes
[Objective] To analyze the causes and distribution characteristics of leukopenia in apheresis platelet donors, and to formulate effective pre-donation intervention measures.
LIANG Yingmei   +4 more
core   +1 more source

More than just anemia: Uncovering celiac disease beneath the surface: A case report

open access: yesJPGN Reports, EarlyView.
Abstract Celiac disease (CD) is an immune‐mediated disorder triggered by gluten in genetically susceptible individuals. Although iron deficiency anemia is a common presentation, other micronutrient deficiencies may occur. We describe a 3.5‐year‐old female whose initial presentation of CD was severe, asymptomatic normocytic anemia secondary to copper ...
Evan Greenhall   +3 more
wiley   +1 more source

Leukopenia and thrombocytopenia by fever day.

open access: yes, 2016
Leukopenia and thrombocytopenia by fever day.
Hadi Jusuf (421615)   +15 more
core  

Table_1_NUDT15 R139C Variants Increase the Risk of Azathioprine-Induced Leukopenia in Chinese Autoimmune Patients.doc

open access: yes, 2018
The aim of this study was to investigate the influence of NUDT15 R139C, thiopurine S-methyltransferase (TPMT), and 6-TGN on azathioprine (AZA) induced leukopenia in Chinese autoimmune patients. Among 87 enrolled patients, 23 (26.4%) had leukopenia.
Shiying Wang (5179559)   +7 more
core   +1 more source

Beyond the gut: Non‐specific interstitial pneumonia in pediatric ulcerative colitis—A rare extra‐intestinal manifestation

open access: yesJPGN Reports, EarlyView.
Abstract Inflammatory bowel disease (IBD) is a chronic inflammatory disorder often presenting with extra‐intestinal manifestations (EIMs) involving the skin, joints and eyes. However, pulmonary manifestation, such as interstitial lung disease (ILD), is a rare complication, particularly in the pediatric population. We report a case of a 10‐year‐old boy,
Harshit Vachher   +5 more
wiley   +1 more source

From treating UTI to agranulocytosis

open access: yesJournal of Family Medicine and Primary Care
The growing problem of antibacterial resistance has resulted in increased interest in fosfomycin, especially its parenteral formulation. It is a broad-spectrum antibiotic with both in vivo and in vitro activity against a wide range of bacteria, including
Amit Katyal   +3 more
doaj   +1 more source

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