Results 81 to 90 of about 64,598 (305)

From treating UTI to agranulocytosis

Journal of Family Medicine and Primary Care
The growing problem of antibacterial resistance has resulted in increased interest in fosfomycin, especially its parenteral formulation. It is a broad-spectrum antibiotic with both in vivo and in vitro activity against a wide range of bacteria, including
Amit Katyal, Nikunj Tiwari, Vaka Rajshekhar, Maninder P. S. Pardal   +3 more
doaj   +1 more source

Table_1_NUDT15 R139C Variants Increase the Risk of Azathioprine-Induced Leukopenia in Chinese Autoimmune Patients.doc

, 2018
The aim of this study was to investigate the influence of NUDT15 R139C, thiopurine S-methyltransferase (TPMT), and 6-TGN on azathioprine (AZA) induced leukopenia in Chinese autoimmune patients. Among 87 enrolled patients, 23 (26.4%) had leukopenia.
Shiying Wang (5179559), Qing Shu (584429), Weihong Ge (5179556), Bingzhu Hua (293565), Ling Guo (9700), Huaijun Zhu (5179562), Xiang Fei (277665), Yun Fang (502174)   +7 more
core   +1 more source

173. Does the correlation between chemotherapy-induced leukopenia with response in locally advanced breast cancer exist? [PDF]

, 2003
PurposeThe correlation between chemotherapy-induced toxicity and treatment outcome in cancer patients has not been thoroughly studied. Our aim was to evaluate whether leukopenia following primary chemotherapy may be predictive for response in patients ...
J. Jassem, Badzio, A., M. Wełnicka-Jaśkiewicz, Tomczak-Hałaburda, J., J. Tomczak-Hałaburda, Jereczek-Fossa, B., B. Jereczek-Fossa, Wełnicka-Jaśkiewicz, M., W. Rogowski, Jassem, J., A. Badzio, Rogowski, W.   +11 more
core   +1 more source

DPYD and UGT1A1 Genotype‐Based Dosing for Fluoropyrimidines and Irinotecan Chemotherapy: Variant‐Specific Impact on Treatment Intensity and Toxicity

International Journal of Cancer, EarlyView.
Pre‐treatment DPYD and UGT1A1 genotyping is increasingly used to prevent fluoropyrimidine‐ and irinotecan‐related toxicity, but variant‐specific real‐world effects remain unclear. In an unselected cohort of cancer patients with actionable genotypes, genotype‐driven dosing improved safety while preserving treatment exposure in high‐risk DPYD c.1905+1G>A
Martina Gambron, Elena Peruzzi, Samantha Perfler, Marcella Montico, Riccardo Cecchin, Elena De Mattia, Michele Spina, Camilla Lisanti, Serena Corsetti, Luisa Foltran, Fabio Puglisi, Rossana Roncato, Erika Cecchin   +12 more
wiley   +1 more source

Prognostic significance of leukopenia during the induction phase in adult B cell acute lymphoblastic leukemia

, 2018
Chongyun Xing,1,* Bin Liang,1,* Junqing Wu,1 Qianqian Yang,1 Gang Hu,1 Ye Yan,1 Yu Zhang,1 Songfu Jiang,1 Kang Yu,1 Jianhua Feng1,2 1Division of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, PR China; 2Division of ...
Wu J, Feng J, Hu G, Zhang Y, Xing C, Jiang S, Yang Q, Yan Y, Yu K, Liang B   +9 more
core  

Forest plot of meta-analysis for leukopenia (grade 3/4).

, 2018
Forest plot of meta-analysis for leukopenia (grade 3/4).
Zhao Dehua (4989911), Chu Mingming (4989914), Wang Jisheng (4989917)   +2 more
core   +1 more source

N6‐Methyladenosine in Inflammatory Bowel Disease: An Emerging Regulator of Pathogenesis and a Novel Therapeutic Frontier

iMetaMed, EarlyView.
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo, Yang Zhang, Xin Wang, Shan Cao, Jun Xu   +4 more
wiley   +1 more source

Anemia Due to Unexpected Zinc-Induced Copper Deficiency

Hematology Reports
Anemia due to acquired copper deficiency is most commonly the result of malabsorption or dietary deficiency. However, it can occasionally be due to excess zinc intake, which impairs the absorption of copper.
Nicholas Chun, Shehla Aman, Dan Xu, Jun Wang, Craig Zuppan, Albert Kheradpour   +5 more
doaj   +1 more source

Severe leukopenia in Staphylococcus aureus-necrotizing, community-acquired pneumonia: risk factors and impact on survival. [PDF]

, 2013
International audienceBACKGROUND: Necrotizing pneumonia attributed to Panton-Valentine leukocidin-positive Staphylococcus aureus has mainly been reported in otherwise healthy children and young adults, with a high mortality rate.
Khanafer, Nagham, Nicolas Sicot, Jérôme Etienne, Michèle Bès, Dumitrescu, Oana, Gillet, Yves, Yves Gillet, Gérard Lina, Tristan, Anne, François Vandenesch, Etienne, Jérôme, Vandenesch, François, Lina, Gérard, Meyssonier, Vanina, Oana Dumitrescu, Bès, Michèle, Philippe Vanhems, Anne Tristan, Vanina Meyssonier, Sicot, Nicolas, Vanhems, Philippe, Nagham Khanafer   +21 more
core   +2 more sources

Development and External Validation of Logistic Regression Models Integrating Conventional Complete Blood Count and Cell Population Data for Predicting RT‐PCR–Confirmed Dengue

Journal of Clinical Laboratory Analysis, EarlyView.
We developed logistic regression models integrating routine complete blood count (CBC) parameters and analyzer‐derived cell population data (CPD) to predict RT‐PCR–confirmed dengue infection and evaluated their performance across internal and external settings.
Lin‐Chen Hsu, Yu‐Ching Weng, Wen‐Chun Liu   +2 more
wiley   +1 more source