Results 61 to 70 of about 1,159,991 (294)
Level Crossings for Random Fields
For an $n$-dimensional random field $X(\mathbf{t})$ we define the excursion set $A$ of $X(\mathbf{t})$ by $A = \{\mathbf{t} \in \mathbf{I}_0: X(\mathbf{t}) \geqq u\}$, where $I_0$ is the unit cube in $R^n.$ It is shown that the natural generalisation of the number of upcrossings of a one-dimensional stochastic process to random fields is via the ...
Adler, Robert J., Hasofer, A. M.
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Quantum search algorithms on a regular lattice
Quantum algorithms for searching one or more marked items on a d-dimensional lattice provide an extension of Grover's search algorithm including a spatial component.
A. Ambainis +6 more
core +1 more source
Global k-Level Crossing Reduction
Summary: Directed graphs are commonly drawn by a four phase framework introduced by \textit{K. Sugiyama} et al. in 1981 [IEEE Trans. Syst., Man, Cybern. 11, No. 2, 109--125, (1981)]. The vertices are placed on parallel horizontal levels. The edge routing between consecutive levels is computed by solving one-sided 2-level crossing minimization problems,
Bachmaier, Christian +3 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Level Crossing in Random Matrices: I. Random perturbation of a fixed matrix
We consider level crossing in a matrix family $H=H_0+\lambda V$ where $H_0$ is a fixed $N\times N$ matrix and $V$ belongs to one of the standard Gaussian random matrix ensembles.
Shapiro, B., Zarembo, K.
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
pedestrian railway crossing, level crossing, traffic safety, pedestrian, accident rate coefficient
Applying the Ishikawa and the Bow-Tie techniques to identify root causes in a real-life passenger injury case while boarding a suburban train is examined, the effectiveness of existing control measures (barriers) is analyzed, and new ones are proposed in
Yaroslav Bolshelarskyi +4 more
doaj +1 more source
Crossing Levels: Meta-induction and the Problem of Induction
AbstractGerhard Schurz claims to have a solution to Hume’s problem of induction based on results from machine learning concerning meta-induction. His argument has two steps. The first is to establish a justification for following a certain meta-inductive strategy based on its predictive optimality.
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