Results 81 to 90 of about 258,282 (264)
Assessment of the accident rate coefficient at pedestrian railway crossings
Transport TechnologiesThe object of the study is pedestrian railway crossings, which are specially designed pedestrian paths across railway tracks intended to ensure the safe passage of pedestrians over railway infrastructure, including areas outside of official level ...
Julia Lesiv, Vitalii Kovalchuk
doaj +1 more source
Vibroisolation of railway crossings with the application of shape-memory elements [PDF]
Transport Problems, 2009 This research presents existing problem of railway elements and motor –vehicle road elements at their intersections. The objects of simulation research were vehicles passing over a level crossing of automobile road and rail-transportation road. Objective
Jan TARGOSZ
doaj
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Level-Crossing Characteristics of an Actively Managed Buffer
Journal of Sensor and Actuator NetworksIn this paper, we examine a buffer with active management that rejects packets basing on the buffer occupancy. Specifically, we derive several metrics characterizing how effectively the algorithm can prevent the queue of packets from becoming too long ...
Andrzej Chydzinski
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Research on the city tram collision at a level crossing
Advances in Mechanical Engineering, 2018 The collision simulation between a city tram and a car at a level crossing is carried out based on the multi-body dynamics. Compared with the finite element method, this method has an obvious advantage of fast computation speed, so that it is convenient ...
Hechao Zhou +3 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Experimental tests of vehicle body accelerations at selected road and rail crossings
MATEC Web of Conferences, 2019 Vehicles moving across the railway are exposed to the dynamic reaction of unevenness of surface on those level crossing. This significantly influences on the increase of the acceleration as well as forces values transferred to the body of the car.
Waluś Konrad J. +3 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source