Results 101 to 110 of about 258,282 (264)
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Driver Compliance With, and Understanding Of, Level Crossing Controls
Journal of Road Safety, 2010 Since the early 1970s, in an effort to improve road safety, Australian railway authorities have made a concerted effort to reduce the number of level road-rail crossings, particularly those controlled by passive devices such as ‘give way’ or ‘stop’ signs.
C Rudin-Brown +5 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Attention, a level crossing is approaching
Acta PolytechnicaAccidents at level crossings are among the most serious transport collisions, given the severe consequences of these incidents, both material and, sadly, often fatal.
Radek Pavelka
doaj
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Railway level crossing traffic safety based on economic-technical analysisand photogrammetric method
Roads and BridgesThe article characterizes railway-road level crossings in terms of safety measures and pavement types used. Cost analysis of various level crossing safety devices and pavement types was conducted in order to determine the most advantageous solutions in ...
Marcin Bilski +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Assessment of accident rate at lithuanian railways level crossings
Nauka ta progres transportu, 2013 Purpose. The most pressing problem facing the rail traffic safety experts is an accident rate at the railway level crossings. The purpose is to investigate the circumstances, which affect traffic safety at the level crossings, and to offer effective ...
Lionginas Liudvinavichius +1 more
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