Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Texas Low-Level Radioactive Waste Disposal Facility: Economic Analysis January 1984
, 1984 Report of the design of a low-level radioactive waste disposal facility and summarized information relating to the economic impact and ...
Texas Low-Level Radioactive Waste Disposal Authority
core
Monthly sea level from coastal tide gauge station Lord_Howe-A, 1958-1967 (Research quality database)
, 2006 Monthly sea level from coastal tide gauge station Lord_Howe-A, 1958-1967 (Research quality ...
WOCE Sea Level, WSL +1 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Monthly sea level from coastal tide gauge station Christmas-A, 1955-1972 (Research quality database)
, 2006 Monthly sea level from coastal tide gauge station Christmas-A, 1955-1972 (Research quality ...
WOCE Sea Level, WSL +1 more
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Daily sea level from coastal tide gauge station Fort_de_France in 1977 (Research quality database)
, 2006 Daily sea level from coastal tide gauge station Fort_de_France in 1977 (Research quality ...
WOCE Sea Level, WSL +1 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Three-Level Secure Smart Protection for Ring Grid-Connected Distributed Generation
EnergiesThe penetration increase in distributed generators (DGs) into smart grids (SGs) will lead to new challenges, especially in protection systems. In the case of ring grids, the behavior of the short-circuit current is affected by DGs, and the medium voltage
Mostafa Bakkar +5 more
doaj +1 more source
, 2006 Monthly sea level from coastal tide gauge station Ko_Taphao_Noi, 1985-2000 (Research quality ...
WOCE Sea Level, WSL +1 more
core +1 more source