Results 131 to 140 of about 5,693,533 (296)

Three-Level Secure Smart Protection for Ring Grid-Connected Distributed Generation

Energies
The penetration increase in distributed generators (DGs) into smart grids (SGs) will lead to new challenges, especially in protection systems. In the case of ring grids, the behavior of the short-circuit current is affected by DGs, and the medium voltage
Mostafa Bakkar, Santiago Bogarra, Felipe Córcoles, Ahmed Aboelhassan, Shuo Wang, Javier Iglesias   +5 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Towards Game Level Generation Through LLM and GAN [PDF]

Annals of computer science and information systems
Filip Martinović, Danijel Mlinarić, Juraj Dončević, Agneza Krajna, Ivica Botički   +4 more
doaj   +1 more source

Coincident Analysis of Photovoltaics Generation and Consumers Consumption Patterns on Distribution Networks

IEEE Access
The purpose of this paper is to investigate the impact of photovoltaic (PV) distributed generations (DGs) on the operational metrics and short-term planning of distribution networks.
Mostafa Esmaeeli, Hadi Afkar, Maryam Majidzadeh, Sajjad Golshannavaz, Amin Yazdaninejadi   +4 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Player Performance Estimation Through Adaptive Puzzle Levels Generation in Game-Based Assessment

International Journal of Serious Games
Estimating players’ abilities without compromising alignment with assessment objectives remains a key challenge in developing Game-Based Assessment (GBA).
Lailatul Husniah, M. Naufal Azzmi. H, Ali Sofyan Kholimi, Umi Laili Yuhana, Eko Mulyanto Yuniarno, Mauridhi Hery Purnomo   +5 more
doaj   +1 more source