Results 91 to 100 of about 19,206,202 (333)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Spatial transcriptomics reveals unique metabolic profile and key oncogenic regulators of cervical squamous cell carcinoma

Journal of Translational Medicine
Background As a prevalent and deadly malignant tumor, the treatment outcomes for late-stage patients with cervical squamous cell carcinoma (CSCC) are often suboptimal.
Limin Zhou, Jiejie Liu, Peipei Yao, Xing Liu, Fei Chen, Yu Chen, Li Zhou, Chao Shen, You Zhou, Xin Du, Junbo Hu   +10 more
doaj   +1 more source

Influence of single shot and continuous peripheral nerve block on opioid consumption and perioperative pain management in patients undergoing total elbow arthroplasty

JSES International
Background: Peripheral nerve block (PNB) is effective for pain management after shoulder arthroplasty. Our study investigated the impact of regional anesthesia on perioperative pain management following total elbow arthroplasty (TEA).
Tamara Babasiz, MD, Michael Hackl, MD, PhD, Sebastian Wegmann, MD, Jan Hockmann, MD, Kai Hoffeld, MD, Lars P. Müller, MD, PhD, Tim Leschinger, MD, PhD   +6 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Association of upper thoracic motion and scapular upward rotation angle with the occurrence of traumatic shoulder dislocation in rugby players

JSES International
Background: The study aimed to elucidate the relationship between reduced thoracic elevation mobility and scapular upward rotation and the occurrence of traumatic shoulder dislocation in rugby players, as this relationship is unclear. Methods: First-year
Takuya Aso, PT, PhD, Masaki Tamura, PT, PhD, Takuya Maeda, PT, PhD, Yu Noguchi, PT, PhD, Shunya Inoue, PT, MS, Tomoyuki Takahashi, PT, MS, Shumpei Furuyama, PT, MS, Kanji Furuya, MD, PhD, Takeyuki Sambe, MD, PhD, Naoya Nishinaka, MD, PhD   +9 more
doaj   +1 more source

Use of plasma lactate level to predict 28-day mortality in non-elderly and elderly sepsis patients based on the MIMIC-III database [PDF]

, 2019
Yihua Dong, Xiaoyang Miao, Yufeng Hu, Yueyue Huang, Jie Chen, Yingru Lu, Jingye Pan   +6 more
openalex   +1 more source

Data from Plasma 25-Hydroxyvitamin D Levels and Survival in Stage III Colon Cancer: Findings from CALGB/SWOG 80702 (Alliance)

, 2023
Qiao-Li Wang, Chao Ma, Chen Yuan, Qian Shi, Brian M. Wolpin, Yin Zhang, Charles S. Fuchs, Jeffrey Meyer, Tyler Zemla, En Cheng, Priya Kumthekar, Katherine A. Guthrie, Félix Couture, Philip Kuebler, Pankaj Kumar, Benjamin Tan, Smitha Krishnamurthi, Richard M. Goldberg, Alan P. Venook, Charles D. Blanke, Anthony F. Shields, Eileen M. O’Reilly, Jeffrey A. Meyerhardt, Kimmie Ng   +23 more
openalex   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Short-term clinical and functional outcomes of distal biceps tendon fixation: all-suture vs. titanium anchors

JSES International
Background: The objective of this study was to evaluate the preliminary clinical and functional outcomes of patients with distal biceps tendon ruptures undergoing surgical fixation using 2 intramedullary all-suture anchors (ASAs) and to compare these ...
Felix Hochberger, MD, Julian Hess, MD, Christian Konrads, MD, Tizian Heinz, MD, Ella Segatz, Maximilian Rudert, MD, Kilian List, MD   +6 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source