Results 101 to 110 of about 34,849,215 (311)

Multi-Material Topology Optimization Taking into Account the Position of Material Interfaces in 3D

Applied Sciences
Multi-material design as a method of lightweight construction enables the targeted use of materials in a component by utilizing the individual material properties.
Robert Renz, Niklas Frank, Albert Albers
doaj   +1 more source

Study on the Shock Wave Characteristics of Spherical and Cylindrical Explosives in Near-field Underwater Explosion [PDF]

Journal of Applied Fluid Mechanics
Underwater explosions are applied across diverse sectors and present considerable risks to marine infrastructures. Therefore, precise prediction of shockwave loading characteristics for various charge shapes during underwater explosions is critical. This
J. Yu, X. P. Zhang, J. Wang, Y. Hao, H. B. Mao   +4 more
doaj   +1 more source

UVI Image Segmentation of Auroral Oval: Dual Level Set and Convolutional Neural Network Based Approach

Applied Sciences, 2020
The auroral ovals around the Earth’s magnetic poles are produced by the collisions between energetic particles precipitating from solar wind and atoms or molecules in the upper atmosphere.
Chenjing Tian, Huadong Du, Pinglv Yang, Zeming Zhou, Libin Weng   +4 more
doaj   +1 more source

Characterizing Level-set Families of Harmonic Functions

, 2019
Families of hypersurfaces that are level-set families of harmonic functions free of critical points are characterized by a local differential-geometric condition.
Ding, Pisheng
core  

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

A nonlinear variational method for signal segmentation and reconstruction using level set algorithm

, 2006
A nonlinear functional is considered in this letter for segmentation and noise removal of piecewise continuous signals containing binary information contaminated with Gaussian noise.
Mahmoodi, Sasan, Sharif, Bayan
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source