Results 111 to 120 of about 4,243,261 (296)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
IEEE Access, 2019 Industrial 4.0 placed higher demands on the field of intelligent equipment monitoring. The transformer is one of the critical power devices, its intelligent monitoring and fault positioning require in-depth studies.
Jiajun Duan +5 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Level-set-based Shape Optimization on Soft Magnetic Composites with Isotropy Constraint
Soft Magnetic Composites (SMCs) demonstrate excellent potentials for electromagnetic applications. The isotropy is one critical feature in designing the composite.
Ren, Xiaotao +4 more
core +1 more source
Extremely Optimized DRLSE Method and Its Application to Image Segmentation
IEEE Access, 2019 This paper proposes an extremely optimized distance regularized level set evolution (EO-DRLSE) method for image segmentation applications within the framework of level set method (LSM), which combines various types of local statistical features and ...
Dengwei Wang
doaj +1 more source
Commentarii Mathematici Helvetici, 1978 The geometry of level sets plays an important role in the analysis of various function-theoretic problems. Often, however, the level sets are so complicated that one must either choose sets associated with special levels (see [3], [4]) or resort to the approximation of level sets by shorter curves (see[l, pp. 550-553]).
Piranian, George, Weitsman, Allen
openaire +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
IEEE Access, 2018 In this paper, we propose a partial differential equation structure that permits an active contour method to obtain intensity inhomogeneous image segmentation. We consider fitted model comprised of local and global energy functions dictated by the scaled
Shafiullah Soomro +2 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source