Results 121 to 130 of about 4,243,261 (296)

Robust topology optimization of compliant mechanism using multiobjective optimization method

open access: yesNihon Kikai Gakkai ronbunshu, 2016
This study evaluates a robust optimum design of a compliant mechanism considering uncertainty of the load direction. For the topology optimization, this study adopts a level set based approach incorporating a fictitious interface energy term.
Atsushi NISHINO   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Flame Front Detection and Curvature Calculation Using Level Set

open access: yes, 2014
A level set method is proposed for flame front detection and curvature calculation on turbulent premixed OH Planar Laser Induced Fluorescence (OH-PLIF) images. The Flame front on an OH-PLIF image is detected by our proposed curve evolution model. In this
Wang, Yue   +4 more
core  

Level sets of derivatives [PDF]

open access: yesPacific Journal of Mathematics, 1979
Boas, R. P., Cargo, G. T.
openaire   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Level-set based Topology optimization using the Continuous Adjoint Method

open access: yes, 2017
In this paper, the development and application of the continuous adjoint of the incompressible Navier-Stokes coupled with the level-set method applied to topology optimization, is presented.
De Villiers, E., (5316757)   +3 more
core   +1 more source

Optic disc segmentation for glaucoma screening system using fundus images

open access: yesClinical Ophthalmology, 2017
Ahmed Almazroa,1,2 Weiwei Sun,3 Sami Alodhayb,4 Kaamran Raahemifar,5 Vasudevan Lakshminarayanan6 1King Abdullah International Medical Research Center (KAIMRC), Riyadh, Saudi Arabia; 2Ophthalmology and Visual Science Department, University of Michigan ...
Almazroa A   +4 more
doaj  

Note on Level Set Functions

open access: yes, 2013
In this note a concept of ε-level set function is introduced, i.e. a function which approximates a level set function satisfying the Hamilton-Jacobi inequality. We prove that each Lipschitz continuous solution of the Hamilton-Jacobi inequality is an ε-level set function.
Piotr Fulmanski, Alicja Miniak-Górecka
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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