Results 111 to 120 of about 34,849,215 (311)
A SEGMENTATION PROBLEM IN QUANTITATIVE ASSESSMENT OF ORGAN DISPOSITION IN RADIOTHERAPY
Image Analysis and Stereology, 2011 Radiotherapeutic treatment of cancer is best conducted if the prescription dose is given to the tumor while surrounding normal tissues are maximally spared.
Giovanni Naldi +6 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Frontiers in Environmental Science, 2019 The objective of this study is to investigate the “inversion approach” for flood defense optimization in an inundated area. This new methodology within this engineering field consists in defining a “safety criterion” (for instance, “the water level in a ...
Yann Richet, Vito Bacchi
doaj +1 more source
Level Sets of Multiparameter Brownian Motions
Electronic Journal of Probability, 2004 The research of Mountford TS is partially supported by the NSF Grant DMS. The research of Nualart E is supported by the Fonds National Suisse.
Nualart, Eulalia, Mountford, Thomas
openaire +4 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
IEEE Access, 2019 Industrial 4.0 placed higher demands on the field of intelligent equipment monitoring. The transformer is one of the critical power devices, its intelligent monitoring and fault positioning require in-depth studies.
Jiajun Duan +5 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Extremely Optimized DRLSE Method and Its Application to Image Segmentation
IEEE Access, 2019 This paper proposes an extremely optimized distance regularized level set evolution (EO-DRLSE) method for image segmentation applications within the framework of level set method (LSM), which combines various types of local statistical features and ...
Dengwei Wang
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
IEEE Access, 2018 In this paper, we propose a partial differential equation structure that permits an active contour method to obtain intensity inhomogeneous image segmentation. We consider fitted model comprised of local and global energy functions dictated by the scaled
Shafiullah Soomro +2 more
doaj +1 more source