Results 191 to 200 of about 2,635,657 (307)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
3D vasculature segmentation using localized hybrid level-set method. [PDF]
Biomed Eng Online, 2014 Hong Q +6 more
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
An improved level set method for vertebra CT image segmentation. [PDF]
Biomed Eng Online, 2013 Huang J, Jian F, Wu H, Li H.
europepmc +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Study of burn scar extraction automatically based on level set method using remote sensing data. [PDF]
PLoS One, 2014 Liu Y, Dai Q, Liu J, Liu S, Yang J.
europepmc +1 more source
Reinitialization for Level Set Methods
, 1998 In the following an introduction to the level set method will be givenso that one becomes aware of the arising problems, which lead to the needof reinitialization. The problems concerning reinitialization itself will be analysed more detailed and a solution for area loss will be proposed. This solution consists in a combination of the commonly used PDE
openaire +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Vascular tree segmentation in medical images using Hessian-based multiscale filtering and level set method. [PDF]
Comput Math Methods Med, 2013 Jin J, Yang L, Zhang X, Ding M.
europepmc +1 more source