Results 111 to 120 of about 4,491,995 (297)

Temporary nurse deployments: a time-series analysis of shift scheduling dynamics and staffing level alignment

International Journal of Nursing Studies Advances
Introduction: Hospitals deploy temporary nurses to bridge staffing gaps. However, evidence remains inconclusive regarding the extent, patterns, and factors driving temporary deployment.
Maryam Ahmadi Shad, MohammadHossein Khorasanizadeh, Sarah N Musy, Franziska Zúñiga, Fatemeh Atoof, Michael Simon   +5 more
doaj   +1 more source

Assessment and comparison of fatigue in shift workers of a rolling mill and a steel production company [PDF]

طب کار, 2013
Background: High levels of fatigue in the workplaces can lead to reduced productivity, and increase the risk of accidents and injuries. Purpose of this study was to assess and compare the fatigue levels among fixed-dayshift and rotating-shift workers of ...
marziye Abbassinia, farogh Mohammadian, mohammadreza Monazam, somaye MahmoodKhani, mahdi Asghari, navid Ghaemian   +5 more
doaj  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Shift work, sleep, and sleepiness - differences between shift schedules and systems

Scandinavian Journal of Work, Environment & Health, 2010
In this narrative review, we examined what level of research evidence is available that shift workers’ sleep–wake disturbances can be minimized through ergonomic shift scheduling.
Mikael Sallinen, Göran Kecklund
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Mental distress among shift workers in Norwegian offshore petroleum industry – relative influence of individual and psychosocial work factors

Scandinavian Journal of Work, Environment & Health, 2011
OBJECTIVE: This study aimed to investigate the association between individual and psychosocial work factors and mental distress among offshore shift workers in the Norwegian petroleum industry. METHODS: All 2406 employees of a large Norwegian oil and gas
Cathrine Haugene Ljoså, Reidar Tyssen, Bjørn Lau   +2 more
doaj   +1 more source

Nurses’ level of sleepiness during night shift

International Nursing Review
AbstractAimsThis study aimed to determine the peak hours of sleepiness and the factors affecting the sleepiness levels of nurses.BackgroundSleepiness is commonly seen in individuals working night shifts. However, in case of nurses, this sleepiness can be a major threat to patient and staff safety.MethodThis was a prospective cross‐sectional study. Data
Ali Kaplan, Cevriye Ozdemir, Emre Bulbul
openaire   +4 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source