Results 71 to 80 of about 4,533,614 (299)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Automatika, 2020 A modified multilevel inverter with a configurable level generation is proposed in this paper. The MLI is composed of a modified boost converter at the front end followed by a level generation circuit and a H-bridge configuration. The front-end converter
Jawahar Rahila, M. Santhi
doaj +1 more source
The origin of the core-level binding energy shifts in nanoclusters
, 2017 We investigate the shifts of the core-level binding energies in small gold nanoclusters by using {\it ab initio} density functional theory calculations. The shift of the 4$f$ states is calculated for magic number nanoclusters in a wide range of sizes and
Abrikosov, Igor A. +2 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Alexandria Engineering JournalTraditional multilevel inverter designs often face complexity challenges, prompting the need for a simplified solution. This study introduces and evaluates the performance of a Modified Packed U-Cells (MPUC) inverter in the realm of multilevel inverter ...
Sherouk Fouda +5 more
doaj +1 more source
Kerr coefficients of plasma resonances in Josephson junction chains
, 2015 We present an experimental and theoretical analysis of the self- and cross-Kerr effect of extended plasma resonances in Josephson junction chains. We calculate the Kerr coefficients by deriving and diagonalizing the Hamiltonian of a linear circuit model ...
Buisson, Olivier +8 more
core +3 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Catastrophic shifts in large lake levels
Fundamental ResearchLarge lakes are important to buffering the potential impacts of global climate change on local water resources that millions of people's livelihoods depend on. However, abrupt changes in water level from one extreme to another (e.g., flood to drought) over short periods of time have been observed recently, threatening aquatic ecosystems and socio ...
Yuanbo Liu +5 more
openaire +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Occupational Fatigue Based on Work Shift Among Medical Workers at Harjono S Hospital
Jurnal Ilmu Kesehatan Masyarakat, 2019 Working at day (morning and afternoon shift) is normal working times according to human physiological conditions, but working at night would impact to the sleep cycle and regulation of human homeostasis.
Dian Afif Arifah +2 more
doaj +1 more source