Results 81 to 90 of about 9,835,184 (256)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
, 2016 Mean reaction time (Standard deviation) for the Vertical-shift-object and Non-vertical-shift-object in the Spatial recall task and the Identity Task across four experiments.
David Uttal (3190695) +2 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Novel level and edge-triggered universal shift registers with low latency in QCA technology
HeliyonShift registers are one of the main blocks in processors. In this paper, two new universal shift registers are designed based on Quantum-Dot Cellular Automata (QCA) nanotechnology.
Mojtaba Gholamnia Roshan +1 more
doaj +1 more source
Occupational Fatigue Based on Work Shift Among Medical Workers at Harjono S Hospital
Jurnal Ilmu Kesehatan Masyarakat, 2019 Working at day (morning and afternoon shift) is normal working times according to human physiological conditions, but working at night would impact to the sleep cycle and regulation of human homeostasis.
Dian Afif Arifah +2 more
doaj +1 more source
Catastrophic shifts in large lake levels
Fundamental ResearchLarge lakes are important to buffering the potential impacts of global climate change on local water resources that millions of people's livelihoods depend on. However, abrupt changes in water level from one extreme to another (e.g., flood to drought) over short periods of time have been observed recently, threatening aquatic ecosystems and socio ...
Yuanbo Liu +5 more
openaire +2 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Tapahtuman asiakaspolun suunnittelu : case SHIFT 2019 [PDF]
, 2019 Työn tavoitteena oli koota kattava tietopaketti tapahtuman asiakaspolkua suunnittelevalle ja esimerkkinä käytettiin SHIFT 2019 tapahtumaa. SHIFT on vuodesta 2016 lähtien toiminut turkulainen yritysfestivaali, jossa tuodaan yhteen eri alojen ...
Aromaa, Milla
core
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source