Results 91 to 100 of about 2,023,090 (375)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Incorporating the Dynamics of Leverage into Default Prediction [PDF]

open access: yes
A firm’s current leverage ratio is one of the core characteristics of credit quality used in statistical default prediction models. Based on the capital structure literature, which shows that leverage is mean-reverting to a target leverage, we forecast ...
Alina Maurer, Gunter Löffler
core  

Peran Mediasi Profitabilitas Terhadap Pengaruh Leverage Dan Ukuran Perusahaan Terhadap Manajemen Laba Riil

open access: yesValue: Jurnal Manajemen dan Akuntansi
By examining operating cash flow anomalies and examining how profitability mediates the impact of leverage and firm size, this study evaluates actual earnings management.
Karjono Karjono, Agoestina Mappadang
doaj   +1 more source

Global Leverage Adjustments, Uncertainty, and Country Institutional Strength

open access: yesJournal of Financial Intermediation, 2017
Using a broad range of uncertainty measures, we show that uncertainty dramatically slows down firms’ adjustments toward their optimal capital structure.
Gonul Colak   +2 more
semanticscholar   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

The determinants of the accounting classification of convertible debt when managers have freedom of choice [PDF]

open access: yes, 2005
This study examines the accounting classification of convertible debt in an environment where there is the choice of debt, other capital funds or equity. Contracting theory suggests possible determinants of accounting choice.
Bishop, Helen E.
core  

Indicators of Financial Analysis Employed in Quantifying the Financial Performance of a Company [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2016
The analysis of the performance of acompany is the most important issue of concern of the management of a company. In order to analyse the performance we use economic and financial indicators which summarizes the level of development and its evolution ...
Mihaela Loredana Ecobici
doaj  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Generalized Soft Breaking Leverage for the MSSM

open access: yes, 2015
In this work we study implications of additional non-holomorphic soft breaking terms (mu', A'_t, A'_b and A'_tau) on the MSSM phenomenology. By respecting the existing bounds on the mass measurements and restrictions coming from certain B-decays, we ...
Kerman, Saime   +3 more
core   +2 more sources

Attention Gated Networks: Learning to Leverage Salient Regions in Medical Images [PDF]

open access: yesMedical Image Anal., 2018
Jo Schlemper   +6 more
semanticscholar   +1 more source

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