Results 81 to 90 of about 548,200 (260)

Using firm level leverage as an investment strategy

open access: yes, 2011
We use an investment strategy based on firm-level capital structures. Investing in low-leverage firms yields abnormal returns of 4.43% per annum. If an investor holds a portfolio of low-leverage and low-market-to-book-ratio firms, abnormal returns ...
Sivaprasad, S.   +3 more
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Forecasting volatility in the presence of Leverage Effect [PDF]

open access: yes
We define a simple and tractable method for adding the Leverage effect in general volatility predictions. As an application, we compare volatility predictions with and without Leverage on the SP500 Index during the period 2002-2010.
Jean-Christophe Domenge   +2 more
core  

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

"Efficient Bayesian Estimation of a Multivariate Stochastic Volatility Model with Cross Leverage and Heavy-Tailed Errors" [PDF]

open access: yes
An efficient Bayesian estimation using a Markov chain Monte Carlo method is proposed in the case of a multivariate stochastic volatility model as a natural extension of the univariate stochastic volatility model with leverage and heavy-tailed errors ...
Yasuhiro Omori, Tsunehiro Ishihara
core   +4 more sources

ANALISIS RASIO KEUANGAN SEBELUM DAN SESUDAH SEASONED EQUITY OFFERINGS (SEO) TERHADAP PENURUNAN KINERJA PASCA PENAWARAN

open access: yesJurnal Analisis Bisnis Ekonomi, 2017
An assesment of work performance is important to be conducted either by the management staffs, stakeholders, goverment and other stakeholders, since it is dealt with the welfare distribution among them.
M Al Amin
doaj  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Leverage Causes Fat Tails and Clustered Volatility [PDF]

open access: yes
We build a simple model of leveraged asset purchases with margin calls. Investment funds use what is perhaps the most basic financial strategy, called "value investing," i.e. systematically attempting to buy underpriced assets.
J. Doyne Farmer   +2 more
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Financial Performance Analysis of Dividends on the LQ45 Index

open access: yesJurnal Maksipreneur: Manajemen, Koperasi, dan Entrepreneurship
Dividend policy is a company's decision to distribute profits between shareholders and the company itself. This study aims to evaluate the influence of factors that determine dividend policy. The independent variables in this study include profitability,
Muhamad Azril Maulana   +4 more
doaj   +1 more source

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