Results 81 to 90 of about 531,323 (307)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Shadow banking and the dynamics of aggregate leverage: An application of the Kalman filter to cyclical leverage measures [PDF]
During the last decades, banks off-balance sheet (OBS) activities (e.g. securitization, trading and fee-based activities) have greatly contributed to the increase in bank risk.
Christian Calmès, Raymond Théoret
core
Determinants of carbon emission disclosure of energy sector companies in Indonesia
Jurnal Ekonomi dan BisnisThis study aims to provide empirical evidence on the effect of profitability, leverage, media exposure, the size of the board of commissioners, and the size of the board of directors on the carbon emissions disclosure of energy companies listed on the ...
Luky Patricia Widianingsih
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
KeunisPrevious empirical findings on the relationship between ESG disclosure and firm value have shown inconsistent results. Some studies suggest that ESG disclosure enhances firm value, while others view it as a cost burden or a managerial tool used for ...
Hendi Rohendi, Yeti Apriliawati
doaj +1 more source
Analysis of the Financial Structure Influence on the Cost of Capital in Multinational Companies [PDF]
Risk in Contemporary Economy, 2012 The main problems identified in determination of financial structure are referred to identifying the source of relevant funds, evaluation of risks generated by using some funds and their costs in order to ensure the autonomy of the enterprise.
Nicoleta BARBUTA-MISU
doaj
Neural Network Approach in Forecasting Realized Variance Using High-Frequency Data
Business Systems Research, 2018 Background: Since high-frequency data have become available, an unbiased volatility estimator, i.e. realized variance (RV) can be computed. Commonly used models for RV forecasting suffer from strong persistence with a high sensitivity to the returns ...
Arnerić Josip +2 more
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
This paper investigates the relation between liquidity and asset prices. It shows that, when banks balance sheets are marked to market and banks are targeting a financial leverage level - a situation similar to current environment - formation of Leverage
Fares Triki
core
"Asymmetry and Leverage in Realized Volatility" [PDF]
A wide variety of conditional and stochastic variance models has been used to estimate latent volatility (or risk). In both the conditional and stochastic volatility literature, there has been some confusion between the definitions of asymmetry and ...
Michael McAleer +2 more
core +4 more sources