Results 81 to 90 of about 223,578 (243)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

HOW FINANCIAL STRENGTH AND INTELLECTUAL CAPITAL DRIVE CORPORATE SOCIAL RESPONSIBILITY - A STAKEHOLDER PERSPECTIVE

open access: yesФінансово-кредитна діяльність: проблеми теорії та практики
This study aims to analyse the effect of profitability (ROE and ROA), leverage (DER), intellectual capital (IC), liquidity (CR), and firm size (FZ) on Corporate Social Responsibility (CSR) in companies listed on the Jakarta Islamic Index (JII).
Mochamad Fahru Komarudin   +3 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

To What Extent Do Regional Effects Influence Firms’ Capital Structure? The Case of Southern Italian SMEs’

open access: yesInternational Journal of Financial Studies, 2019
There is tremendous interest, in the economic literature, for the determinants of firms’ capital structure decisions. A rich body of empirical works now exists that purports to identify firm- and country-level factors affecting firms&rsquo ...
Olivier Butzbach, Domenico Sarno
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Credit Rating as a Mechanism for Capital Structure Optimization: Empirical Evidence from Panel Data Analysis

open access: yesInternational Journal of Financial Studies, 2018
This paper empirically examines the significance of credit ratings for optimal capital structure decisions. Non-financial Asian listed companies, evaluated by Standard and Poor’s, are selected from 2000 to 2016.
Faiza Sajjad, Muhammad Zakaria
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Everyday Leverage, or Leveraging the Everyday [PDF]

open access: yesCultural Studies, 2015
Credit, debt and indebtedness are key terms for understanding contemporary social and economic life. In many recent accounts of debt, however, debt is largely an ahistorical category that remains constant throughout time, or seen simply in terms of a quantum of interest accrued over time that can then serve as a proxy for both the accumulation of ...
openaire   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

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