Results 41 to 50 of about 70,537 (268)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
The Effect Of Taxes, Tunneling Incentives, Bonus Mechanism, Leverage On Transfer Pricing
This study examines the effect of taxes, tunnelling incentives, bonus mechanisms and leverage on transfer pricing decisions in manufacturing companies listed on the Indonesia Stock Exchange (IDX).
C. Susi Maryanti, Agus Munandar
doaj +1 more source
The sales performance of property and real estate companies in Indonesia deteriorated due to uncertain interest rates. Investors, creditors and corporate stakeholders, in this case, especially property and real estate companies, depend on the quality of ...
Arshendy Graha, Khairunnisa Khairunnisa
doaj +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Ensemble CorrDet with adaptive statistics for bad data detection
Smart grid (SG) systems are designed to leverage digital automation technologies for monitoring, control and analysis. As SG technology is implemented in increasing number of power systems, SG data becomes increasingly vulnerable to cyber-attacks ...
Keerthiraj Nagaraj +9 more
doaj +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Pengaruh Corporate Governance Profitabilitas dan Leverage Terhadap Pengungkapan Modal Intelektual
English This study aims to determine the effect of the influence of corporate governance by the independent commissioner and audit committee, profitability and leverage on the disclosure of intellectual capital in the manufacturing companies listed ...
Eny Widyawati
doaj +1 more source
Max-plus statistical leverage scores
The statistical leverage scores of a complex matrix $A\in\mathbb{C}^{n\times d}$ record the degree of alignment between col$(A)$ and the coordinate axes in $\mathbb{C}^n$. These score are used in random sampling algorithms for solving certain numerical linear algebra problems.
openaire +2 more sources
Leveraging quantum statistics to enhance heat engines
Abstract A key focus of designing quantum thermal devices is the potential advantage that can be gleaned from genuine quantum effects when compared to classical devices. The recent experimental realization of the Pauli engine (Koch et al 2023 Nature 621 723)—where energy is extracted via changes in particle statistics ...
Keerthy Menon +2 more
openaire +2 more sources

