Results 51 to 60 of about 3,746 (173)

Primary Varicella Pneumonia in an Adult With Robust Immune Status: A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 7, July 2025.
ABSTRACT Primary varicella‐zoster virus (VZV) infection is infrequent in adults, but it causes more than 10 to 20 times the morbidity and mortality seen in healthy children and pneumonia being the most prevalent consequence. Early recognition and aggressive management of primary varicella pneumonia with antiviral therapy and supportive care is ...
Sunil Bhatta   +2 more
wiley   +1 more source

Exploring the impact of chronic urticaria profile as a key predictor of alexithymia: A cross‐sectional study

open access: yesClinical and Translational Allergy, Volume 15, Issue 7, July 2025.
Abstract Introduction The relationship between chronic urticaria (CU) and alexithymia, a cognitive‐affective impairment characterized by difficulty in identifying and expressing emotions, is complex and underexplored. This study aimed to identify predictors of alexithymia in CU patients by focusing on the impact of coexisting mental illnesses and ...
Ivan Cherrez‐Ojeda   +29 more
wiley   +1 more source

THE EVALUATION OF THE INFLUENCE OF CETRILEV (LEVOCETIRIZINE) ON THE LATE PHASE OF THE ATOPIC REACTION

open access: yesМедична наука України, 2018
Relevance. Previously demonstrated inhibitory effect of levocetirizine on the activity of eosinophils during the late phase of the atopic reaction, but the effect of the drug on the second component of the late phase – lymphocytes – is still not ...
D.V. Maltsev
doaj   +1 more source

Elranatamab for Relapsed/Refractory Multiple Myeloma With Severe Renal Impairment Requiring Hemodialysis

open access: yesHematological Oncology, Volume 43, Issue 4, July 2025.
ABSTRACT Relapsed/refractory multiple myeloma (RRMM) patients with dialysis‐dependent renal impairment face limited therapeutic options due to exclusion from clinical trials, a lack of evidence‐based guidelines, and inferior outcomes. Bispecific antibodies targeting B‐cell maturation antigen (BCMA) have shown promise in RRMM treatment but remain ...
Michèle Hoffmann   +7 more
wiley   +1 more source

A case of chronic spontaneous urticaria with wheals lasting for more than a week

open access: yesThe Journal of Dermatology, Volume 52, Issue 2, Page 344-347, February 2025.
Abstract Urticaria is characterized by the development of wheals which usually disappear within a day, and are not present beyond a few days. A 58‐year‐old man began to develop edematous, partially ring‐shaped erythematous lesions accompanied by severe body itching without any particular cause, approximately 2 months before his first visit to our ...
Satoshi Morioke   +3 more
wiley   +1 more source

Efficacy and safety of the emedastine patch, a novel transdermal drug delivery system for allergic rhinitis: Phase III, multicenter, randomized, double-blinded, placebo-controlled, parallel-group comparative study in patients with seasonal allergic rhinitis

open access: yesAllergology International, 2018
Background: The emedastine patch was developed in Japan as the first transdermal drug delivery system of emedastine difumarate for allergic rhinitis.
Kimihiro Okubo   +5 more
doaj   +1 more source

Histamine Modulation of the Basal Ganglia Circuitry in the Motor Symptoms of Parkinson's Disease

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 2, February 2025.
ABSTRACT Purpose of Review Parkinson's disease (PD) is characterized by dopaminergic system dysfunction that results from the degeneration of neurons in the substantia nigra. However, studies suggest that other neurotransmitters, especially histamine, may also play a role in the development of PD.
Hui‐Xian Zhu   +9 more
wiley   +1 more source

POSSIBILITIES OF USE OF THE MODERN ANTIHISTAMINE MEDICINES IN THERAPY OF PATIENTS WITH ALLERGIC RHINITIS

open access: yesМедицинский совет, 2017
Allergic rhinitis as one of the most common non-infectious respiratory inflammatory diseases is a global public health problem. The course of allergic rhinitis, its effect on the pathology of other organs and systems, the likelihood of complications and ...
G. N. Nikiforova   +3 more
doaj   +3 more sources

Population pharmacokinetic modelling of cetirizine concentrations in human breast milk—A contribution from the ConcePTION project

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 136, Issue 1, January 2025.
Abstract Cetirizine is an antihistamine commonly used to treat allergic rhinitis and other allergic conditions. Cetirizine is often prescribed to breastfeeding mothers although there is limited information on infant exposure via breast milk. The aim of this study was to develop a popPK model based on data from a lactation study to predict cetirizine ...
Erik Melander   +10 more
wiley   +1 more source

Development of the Japanese Anticholinergic Risk Scale: English translation of the Japanese article

open access: yesGeriatrics &Gerontology International, Volume 25, Issue 1, Page 5-13, January 2025.
Background Anticholinergic burden, reflecting the cumulative impact of medications with anticholinergic properties, significantly predicts adverse drug reactions and geriatric syndromes in older adults. Although anticholinergic risk scales (ARS) have been developed and validated in various countries, none have been tailored specifically for Japan.
Fumihiro Mizokami   +15 more
wiley   +1 more source

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