Levocetirizine and Prednisone Are Not Superior to Levocetirizine Alone for the Treatment of Acute Urticaria: A Randomized Double-Blind Clinical Trial [PDF]
We evaluate the efficacy of a 4-day course of prednisone added to antihistamine for the management of acute urticaria in an emergency department (ED).In this double-blind randomized clinical trial, patients were eligible for inclusion if aged 18 years or older and with acute urticaria of no more than 24 hours' duration. Patients with anaphylaxis or who
Caroline Barniol+5 more
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Fixed drug eruption to cetirizine with positive lesional patch tests to the three piperazine derivatives [PDF]
BACKGROUND: The H1-antihistamine cetirizine, a piperazine derivative widely used in daily practice, is rarely the cause of cutaneous drug reaction.
Cravo, M+2 more
core +1 more source
Dietary supplementation with probiotics alters intestinal microflora of children and may have immunomodulatory effects in prevention of allergic diseases. The aim of this study was to evaluate the effects of Lactobacillus paracasei (LP), strain HF.A00232,
Wen-Ya Lin+4 more
doaj +1 more source
H1-antihistamines for chronic spontaneous urticaria: An abridged Cochrane Systematic Review [PDF]
Background Chronic spontaneous urticaria is characterized by recurrent itchy wheals. First-line management is with H1-antihistamines. Objective We sought to conduct a Cochrane Review of H1-antihistamines in the treatment of chronic spontaneous ...
Alomar+119 more
core +1 more source
The Efficacy of Levocetirizine in Allergic Rhinitis in Children
Controversies about the preferred treatment of mild persistent or mild-to-moderate intermittent allergic rhinitis were considered in the study involved 62 primary school childrenю They were randomized to receive oral formulation of levocetirizine (5 mg ...
S.L. Nyankovsky+5 more
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The Contribution of National Spontaneous Reporting Systems to Detect Signals of Torsadogenicity: Issues Emerging from the ARITMO Project [PDF]
Introduction: Spontaneous reporting systems (SRSs) are pivotal for signal detection, especially for rare events with a high drug-attributable component, such as torsade de pointes (TdP).
Antoniazzi, S. (Stefania)+12 more
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Background: Oral antihistamines are considered the gold standard therapy for allergic rhinitis to date. The goal of this investigation is to make an indirect comparison between loratadine, an oral antihistamine available over-the-counter (OTC) in the USA,
Ralph Mösges+2 more
doaj +1 more source
Fixed drug eruption due to levocetirizine
A fixed drug eruption (FDE) is a cutaneous adverse drug reaction due to Type IV or delayed cell-mediated hypersensitivity. Antihistamines, which antagonize the action of histamine during an allergic reaction by blocking the H1 histamine receptors, are used routinely for the treatment of various allergic disorders such as urticaria, eczemas, and also in
Dinesh P Asati+2 more
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Hydrophilic interaction chromatography (HILIC) for the determination of cetirizine dihydrochloride [PDF]
A stability-indicating high-performance liquid chromatography (HPLC) of hydrophilic interactions was developed and validated for the determination of cetirizine dihydrochloride in bulk substance and in pharmaceutical dosage form.
Cielecka-Piontek, Judyta+5 more
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Levocetirizine in clinical practice of allergist
Levocetirizine is an effective H1-blocker of histamine receptors in complex treatment of various allergic diseases. The article presents the literature data and own observational data on clinical efficacy and safety of levocetirizine in the treatment of allergic diseases such as allergic rhinitis, bronchial asthma, allergic dermatoses.
Olga Elisyutina, O V Shtyrbul
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